23 Hair And Nail Disorders

November 2025

alopecia areata androgenetic alopecia telogen effluvium cicatricial alopecia hair transplantation topical medications oral medications genetic factors hormonal factors autoimmune factors

TLDR Hair and nail disorders can harm self-esteem, but early treatment helps.

Hair and nail disorders significantly affect individuals' well-being and self-confidence, with common hair disorders including alopecia areata, androgenetic alopecia, telogen effluvium, and cicatricial alopecia, often caused by genetic, hormonal, autoimmune, or external factors. Treatments typically involve topical and oral medications or hair transplantation. Common nail conditions include onychomycosis, psoriasis, lichen planus, and bacterial infections, which alter nail color, texture, and structure. Early diagnosis and management are crucial in reducing the impact of these disorders.

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Research cited in this study

10 / 10 results

research Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics

17 citations , November 2021 in “Journal of Cosmetic Dermatology”

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

research Acne Keloidalis Nuchae: Prevalence, Impact, and Management Challenges

59 citations , December 2016 in “Clinical, Cosmetic and Investigational Dermatology”

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

research Primary Cicatricial Alopecia

65 citations , November 2016 in “Journal of The American Academy of Dermatology”

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

research Hirsutism: Diagnosis and Treatment

26 citations , March 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia”

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

research Characteristics of Androgenetic Alopecia in Asian Populations

51 citations , January 2012 in “Annals of Dermatology”

Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.

research Chronic Telogen Effluvium Is Due to a Reduction in the Variance of Anagen Duration

40 citations , May 2010 in “Australasian Journal of Dermatology”

Chronic hair shedding may be caused by less variation in hair growth times and might stop on its own after several years.

research Early Diagnosis and Treatment of Discoid Lupus Erythematosus

61 citations , March 2009 in “The Journal of the American Board of Family Medicine”

Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.

research Lichen Planopilaris: Update on Diagnosis and Treatment

160 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

research Multifactorial Classification of Male and Female Androgenetic Alopecia

32 citations , June 2000 in “Dermatologic Surgery”

Different factors help diagnose and treat hair loss accurately.

research Folliculitis Decalvans Including Tufted Folliculitis: Clinical, Histological, and Therapeutic Findings

226 citations , February 1999 in “British Journal of Dermatology”

Folliculitis decalvans and tufted folliculitis are related, and a new treatment with rifampicin and clindamycin is effective.

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6 / 1000+ results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 3 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community can someone please tell me its going to get better? im bawling my eyes out

in Female 67 upvotes 3 years ago

A 16-year-old girl is experiencing hair loss, which has worsened despite using minoxidil and multivitamins. Suggestions include broader hormone testing and considering other treatments like spironolactone if the hair loss is due to androgenic alopecia.

community 2 months progress. Hair is shorter in the first pic, same length in the second and third.

in Progress Pictures 294 upvotes 2 years ago

User reports 2 months progress using daily oral fin 1mg, twice daily topical min 5%, and intermittent dermapen. Others share their experiences, suggesting patience and additional treatments like alternating shampoos, using conditioner, tretinoin, and vitamins.

community Hairline stable but diffuse thinning with topical fin+min

schiz_narc_trev in Finasteride 237 upvotes 3 weeks ago

The user experienced stable hairline but diffuse thinning after switching from oral finasteride to a topical solution of minoxidil and finasteride. They are concerned about the effectiveness of the topical treatment and are considering other options due to a recent decline in hair density.

Similar Research

6 / 1000+ results

research Hair Disorders

October 2018 in “Springer eBooks”

The document concludes that various hair disorders have different treatments, including medication, surgery, and addressing underlying causes.

research Hair Loss And Its Management In Children

5 citations , November 2011 in “Expert Review of Dermatology”

The document concludes that early diagnosis and a comprehensive treatment plan are crucial for managing hair loss in children, with a focus on both medical and psychological support.

research Evaluation of Hair Loss

5 citations , January 2015 in “Current problems in dermatology”

The document concludes that a thorough history, physical exam, and specific tests are crucial for diagnosing and managing hair loss effectively.

research Female Adolescent Hair Disorders

20 citations , July 2009 in “Journal of Pediatric and Adolescent Gynecology”

Quick treatment of hair disorders in teenage girls is important because of the emotional effects.

research Management of Hair Loss Diseases

14 citations , December 2010 in “Dermatologica Sinica”

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

research Alopecia

January 2018 in “Elsevier eBooks”

The document concludes that alopecia has various forms, each with specific treatments, but no definitive cure for certain types like CCCA has been proven.