April 201411
Sulfotransferase activity in plucked follicles predicted response to 5% minoxidil in women with pattern hair loss, with 93% sensitivity and 83% specificity. In mice, the herbal mixture CARI ONE induced anagen and outperformed 1% minoxidil. A TLR1 variant was associated with susceptibility to alopecia areata in a Korean case-control study. In a lab model, early-passage human keratinocytes grafted onto mice formed new hair follicles.
- Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia In women with pattern hair loss, sulfotransferase activity in plucked hair follicles predicted response to 5% minoxidil with 93% sensitivity and 83% specificity.
- The endocrinology of baldness a review of the endocrinology of baldness.
- CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis In mice, the herbal mixture CARI ONE promoted hair growth by inducing the anagen phase via beta-catenin, outperforming 1% minoxidil in this model.
- Association between TLR1 polymorphisms and alopecia areata A TLR1 gene variant (rs4833095) was associated with susceptibility to alopecia areata in a Korean case-control study.
- A model system to analyse the ability of human keratinocytes to form hair follicles A lab model using early-passage human keratinocytes grafted onto mice produced new hair follicles, offering a tool to study follicle formation.
- Modulating hair follicle size with <i>Wnt10b/DKK1</i> during hair regeneration In mice, Wnt10b enlarged regenerating hair follicles and the inhibitor DKK1 reversed this, showing Wnt signaling controls follicle size.
- Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia Mice lacking ceramide synthase 4 developed altered sebum lipids and progressive hair loss from blocked hair canals.
- Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long-term follow-up In a 62-patient retrospective cohort of frontal fibrosing alopecia, intralesional corticosteroids stabilized the hairline in 97% of treated patients.
- Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth In mice, Wharton's jelly stem cells on an amniotic membrane scaffold improved scar-free wound healing with hair regrowth.
- Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors In human hair follicles, graying was linked to reduced catalase and antioxidant activity affecting both mature and precursor melanocytes.
- A Systematic Approach to Afro-Textured Hair Disorders A review of what is known about dermoscopic (trichoscopy) findings in Afro-textured hair disorders.