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research Directional Pressure Pump Hydrogel Transmission Platform Provides Bionic Contractile Force and Remodels the Healing Process for Diabetic Mechanically Dynamic Wounds
This study developed a directional pressure-pump hydrogel delivery platform that enhances wound healing in diabetic mechanically dynamic wounds by targeting antibacterial agents and nanozymes directly to the lesion site, disrupting biofilms, mitigating tissue damage, and supporting proper skin closure and vascular remodeling in animal models.
research Early and Midterm Outcome After Off-Pump and On-Pump Surgery in Beating Heart Against Cardioplegic Arrest Studies (BHACAS 1 and 2): A Pooled Analysis of Two Randomized Controlled Trials
This study found that off-pump coronary surgery significantly reduces in-hospital morbidity compared to on-pump surgery without affecting midterm outcomes in the first 1-3 years after the procedure.
research Comprehensive Treatment of Cronkhite-Canada Syndrome: A Case Report and Literature Review
This review discusses the potential of traditional Chinese medicine to relieve clinical symptoms in cases of CCS and emphasizes the need for further large-scale, long-term studies to verify these effects.
research Case of Cronkhite-Canada Syndrome Shows Improvement with Enteral Supplements
This case report describes a 33-year-old Indian male with Cronkhite-Canada syndrome who experienced complete symptom recovery within 5 months after starting a high protein diet, proton pump inhibitors, and zinc-vitamin supplements.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
research Omeprazole-Induced Hypertrichosis in Two Children
This study found that omeprazole can cause acquired generalized hypertrichosis by significantly increasing duodenal prostaglandin E2 synthesis, which is involved in hair growth regulation.
research Unexpected Hypozincaemia in a Patient with Discharging Empyema Resistant to Replacement Therapy
In this case study, zinc deficiency persisted despite supplementation in a patient with severe malnutrition and empyema, potentially due to nutrient absorption competition and proton pump inhibitor use.
research Black Hairy Tongue Syndrome: Case Report and Review of the Literature
In this case report and literature review, researchers observed that black hairy tongue syndrome can be improved by dietary restrictions and local care, identifying factors like antibiotics, malignancies, and certain medications as common triggers, with resolution achieved by eliminating these factors when possible.
research An Unusual Case of Diarrhea, Dysgeusia, and Grainy and Nodular Mucosa
This study describes the diagnosis and successful management of Cronkhite-Canada syndrome in a 78-year-old man, highlighting improvement in symptoms and endoscopic findings after treatment with prednisone and supportive therapies.
research Factors to Consider When Selecting Antiulcer Drugs for a Formulary
The document concludes that H2-antagonists and proton pump inhibitors are highly effective for ulcers, eradicating Helicobacter pylori is important to prevent recurrence, and misoprostol helps with NSAID-related ulcers.
research Insulin Pump Therapy: Accu-Chek FlexLink Plus, The First Self-Retracting Needle Catheter and Accu-Chek LinkAssist Plus
The Accu-Chek FlexLink Plus and Accu-Chek LinkAssist Plus make insulin pump use safer, simpler, and more comfortable.
research A Computer-Aided Drug Repurposing: The Antibacterial Agents Targeting GroEL
In this study, researchers validated a computational workflow for repurposing non-antibacterial drugs as antibacterial agents and highlighted daprodustat, combined with an efflux pump inhibitor, as a promising strategy against bacterial pathogens.
research Miscellaneous Topics in Disorders of Endocrine Glands
This chapter reviews the pathophysiology of immune checkpoint inhibitor-related endocrinopathies and examines the rationale for using advanced diabetes care technologies, like pump therapies and continuous glucose monitors, in managing these conditions.
research The Resistance Mechanisms of Bacteria Against Ciprofloxacin and New Approaches for Enhancing the Efficacy of This Antibiotic
This review discusses ciprofloxacin resistance mechanisms in bacteria and explores new approaches, such as combining it with other antibacterial agents, to enhance its effectiveness against resistant infections.
research Selective Follicular Targeting by Modification of the Particle Sizes
This study found that medium-sized particles (643 and 646 nm) penetrated deeper into porcine hair follicles in vitro than smaller or larger particles, suggesting size-selective targeting within follicular sites.
research Chronic Pancreatitis and Persistent Steatorrhea: What Is the Correct Dose of Enzymes?
This article reviews current therapies for exocrine pancreatic insufficiency in chronic pancreatitis, highlighting the challenges in achieving optimal enzyme dosing and the potential need for treatment even in asymptomatic patients.
research Investigation of Differences in Follicular Penetration of Particle- and Nonparticle-Containing Emulsions by Laser Scanning Microscopy
In this study, particles similar in size to keratin cells were surprisingly found to penetrate more efficiently into hair follicles due to a possible pumping effect from moving hairs.
research Improving the Treatment of Bacterial Infections Caused by Multidrug-Resistant Bacteria Through Drug Repositioning
This review examines drug repositioning as a strategy for combating bacterial infections, highlighting its potential to address multidrug-resistant strains and antibiotic resistance by analyzing safety profiles, synergistic combinations, and promising results for drugs initially used for other conditions.
research Inconsolable Crying in Infants: Differential Diagnosis in the Pediatric Emergency Department
Most inconsolable crying in infants is not due to a serious cause, and a detailed check-up is typically enough to find the reason.
research Barrett's Esophagus as a Premalignant Condition: Medical and Surgical Therapeutic Management
This review discusses Barrett's esophagus, its risk factors, diagnostic methods, and treatment options, emphasizing its potential for malignant degeneration and the importance of personalized treatment based on patient factors.