I want to add a topical anti androgen to my routine
    9/27/2023

    From the encyclopedia
    RU58841 →

    a potent but unapproved and potentially problematic topical anti-androgen

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Spironolactone →

    powerful topical and oral anti-androgen used mostly by women

    At a glance
    In this question or advice post, the primary subjects mentioned are
    💧 RU58841 (topical) 5%
    💧 Minoxidil (topical)
    💧 Spironolactone (topical)
    💧 Melatonin (topical)
    the tone is 😐 neutral.

    Other terms

    RU58841 is considered an effective topical anti-androgen for hair loss, often used with minoxidil. Concerns exist about its purity and sourcing since it's not FDA-approved.
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    5 / 5 results

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 2 years ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community Recommendations for topical antiandrogens

      in Treatment  2 upvotes 9 months ago
      The conversation is about adding a topical anti-androgen to a hair loss treatment regimen that includes dutasteride and oral minoxidil. The user is considering topical finasteride or dutasteride, Nizoral shampoo, KX-826, and topical spironolactone, while avoiding RU58841 due to safety concerns.

      community Any good experiences with Alfatradiol ?

       4 upvotes 6 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.

      community Breezula is the final brick in the wall

       36 upvotes 2 months ago
      Breezula is discussed as a potential topical anti-androgen treatment for hair loss, with mixed opinions on its effectiveness and side effects compared to other treatments like finasteride, minoxidil, and RU58841. Some users express skepticism about its long-term efficacy and potential side effects, while others are hopeful for its approval and use in combination with existing treatments.

    Related Research

    6 / 6 results

      research Therapeutic strategies for treating hair loss

      42 citations , March 2006 in “Drug Discovery Today: Therapeutic Strategies”
      This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.

      research Investigational medications in the treatment of alopecia

      3 citations , February 2005 in “Expert Opinion on Investigational Drugs”
      This review discusses investigational treatments for androgenetic and chemotherapy-induced alopecia and reports no new clinical results, highlighting the need for further research.

      research What’s new in the treatment of hair loss?

      June 2024 in “Bőrgyógyászati és Venerológiai Szemle”
      In this article, the authors review the most effective current treatments for hair loss, such as Janus Kinase Inhibitors, Platelet Rich Plasma, anti-androgens, and minoxidil, highlighting the expanding therapeutic options for alopecia.

      research Antiandrogens and Androgen Inhibitors

      November 2020 in “Elsevier eBooks”
      This source outlines various antiandrogen and androgen inhibitor drugs used to treat cutaneous disorders of hyperandrogenism, detailing their mechanisms, uses, dosages, and side effects, with emphasis on spironolactone, finasteride, dutasteride, and oral contraceptives.