Anyone here tried topical spironolactone? 8/3/2025
Topical spironolactone was ineffective for hair loss according to one user who tried 2% nightly for a few months. The user reported no results.
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6 / 6 resultscommunity Looking for information on topical spironolactone
Topical spironolactone is considered a promising solution for hair maintenance, with some suggesting it may be more effective than topical finasteride. However, concerns about its odor and lack of research on its efficacy remain.
community Can males use topical spironolactone?
Topical spironolactone is considered safe for males but is not very effective for hair loss. Some users suggest trying it since it's already purchased, while others recommend alternatives like clascoterone.
community Is anyone on topical spironolactone, or has anyone tried this?
Topical spironolactone is discussed as a potential hair loss treatment for those who can't tolerate finasteride, with some users noting varied results and side effects. Alternatives like laser caps are also mentioned.
community Why is nobody talking about topical Spironolactone?
Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.
community Are there any males here that use (or have used) topical spironolactone?
Topical spironolactone is available in the UK for men to block androgen receptors locally. The user seeks opinions or experiences from others who have used it.
community Any male on topical spironolactone?
Topical spironolactone is discussed for hair loss treatment, with mentions of DIY solutions and dermatologist compounding. Users inquire about regrowth and sourcing the treatment.
Related Research
6 / 6 results
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
This study reported that topical spironolactone improved lid margin vascularity, corneal fluorescein staining, and disease severity scores in patients with ocular graft-versus-host disease, suggesting a potential therapeutic role by enhancing corneal lipid production with minimal adverse effects.
research The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review
This study concluded that both oral and topical spironolactone effectively treat androgenetic alopecia, with topical administration being safer and suitable for any gender, especially when combined with minoxidil.
research Topical Spironolactone in the Treatment of Evaporative Dry Eye Disease
In a retrospective study, researchers found that topical spironolactone improved tear film quality and reduced inflammation related to meibomian gland dysfunction and evaporative dry eye in patients, demonstrating good tolerability and suggesting it as a potential therapy for managing the condition.
research Dermoscopic evaluation of the efficacy of combination of topical spironolactone 5% and minoxidil 5% solutions in the treatment of androgenetic alopecia: A cross sectional‐comparative study
This study found that combining 5% topical minoxidil and 5% topical spironolactone solutions may enhance treatment efficacy for androgenetic alopecia in both men and women, with significant reductions in vellus hair.
research The efficacy of the combination of topical minoxidil and oral spironolactone compared with the combination of topical minoxidil and oral finasteride in women with androgenic alopecia, female and male hair loss patterns: A blinded randomized clinical trial
This study found that combining minoxidil and spironolactone was more effective for hair density and severity of hair loss in women with androgenic alopecia compared to minoxidil and finasteride, with no serious adverse effects reported.
research Topical Finasteride versus Topical Spironolactone in the Treatment of Androgenetic Alopecia
In this study, topical spironolactone was found to be more effective than topical finasteride for treating androgenetic alopecia in both males and females, with fewer side effects compared to oral finasteride.