89 citations
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March 2018 in “Journal of Cellular Physiology”
The Wnt/β-cateninpathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-cateninpathway is crucial for hair growth, and JW0061 activates this pathway effectively.
The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signalingpathways and has anti-androgenic effects.
NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.
The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.
A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Cateninsignaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.