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Glossary Vitamin D Metabolism

process converting vitamin D into its active, calcium-regulating form

Vitamin D metabolism refers to the process by which the body converts vitamin D from sunlight or dietary sources into its active form, which is crucial for calcium absorption and bone health. This involves two main steps: first, vitamin D is converted to calcidiol in the liver, and then to calcitriol in the kidneys, which is the biologically active form that helps regulate calcium and phosphate levels in the blood.

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Research

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research A novel LC-MS/MS analysis of vitamin D metabolites in mice serum and hair: impact of diet and light exposure

1 citations , February 2025 in “Frontiers in Endocrinology”

In this study, researchers observed that dietary vitamin D intake and light exposure play a crucial role in vitamin D metabolism in mice, suggesting similar importance for human health in maintaining optimal vitamin D levels.

Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

research Deletion of Deoxyribonucleic Acid Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D

277 citations , July 2002 in “Molecular Endocrinology”

In this study, homozygous VDR null mutant mice exhibited nonfunctional vitamin D receptors, leading to growth abnormalities and revealing the limited physiological importance of vitamin D pathways outside the classical receptor.

research Effects of vinblastine and its metabolites on nausea and alopecia associated receptors

December 2018

This study found that vinblastine's metabolites show binding affinities for receptors linked to nausea and alopecia, suggesting potential changes to its structure could minimize these side effects during chemotherapy.

research UV radiation, vitamin D and epidermal carcinogenesis

December 2009 in “Expert review of dermatology”

This article reviews evidence suggesting that vitamin D and its metabolite may help protect against nonmelanoma skin cancer, but reports no new empirical findings.

research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor α Expression During Squamous Differentiation of Cultured Keratinocytes

15 citations , March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.

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Community Join

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community Does vitamin D deficiency actually cause hair loss? Has anyone actually grew back hair after fixing vitamin d levels?

in Chat 65 upvotes 1 year ago

Vitamin D deficiency can contribute to hair loss, but it is not the sole cause, and supplementation may not always resolve the issue. Treatments like finasteride and minoxidil are recommended for hair regrowth, with vitamin D and other supplements providing additional support.

community Can low level of vitamins cause hair loss?

21 upvotes 2 years ago

The conversation is about whether low vitamin levels can cause hair loss. The consensus is that the user's vitamin levels are normal and unlikely to affect hair loss or the effectiveness of finasteride and minoxidil treatments.

community Dutasteride thins eyebrows and facial hair but doesn't stop scalp loss.

in Finasteride/Dutasteride 37 upvotes 1 year ago

Dutasteride may not effectively stop scalp hair loss and can cause thinning of facial and body hair, including eyebrows. Users suggest considering other causes like autoimmune conditions or vitamin deficiencies and exploring treatments like finasteride or minoxidil.

community Hair Loss Journey so far and where to now (22yo)

in Is this regrowth? 2 upvotes 1 year ago

The user is experiencing hair loss and is using topical finasteride, rosemary oil, caffeine, microneedling, low-level laser therapy, scalp massages, ketoconazole shampoo, and various vitamins and supplements. They are concerned about potential gynecomastia and are considering using minoxidil if current treatments do not stop hair loss or promote regrowth.

community Has any premature balding guys actually saved and maintained their hair?

in Chat 17 upvotes 1 year ago

A user discusses their struggle with aggressive hair loss starting at a young age and their use of various treatments, including topical finasteride, minoxidil, dutasteride, and RU58841, without significant success. Other users share their experiences and suggest trying oral finasteride or dutasteride, topical spironolactone, and maintaining a vitamin regimen, while noting potential side effects like gynecomastia.

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Learn

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learn Overview

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

What is the connection between Vitamin D and hair loss? Vitamin D deficiency may contribute to hair loss by disrupting hair follicle regulation.
Can Vitamin D deficiency trigger excessive hair shedding? Yes, vitamin D deficiency can trigger excessive hair shedding.
Is it safe to take Vitamin D supplements for hair growth? Vitamin D supplements are generally safe but may not significantly improve hair growth.
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learn Calcium D oantothenate

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

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Clinics

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Hair Loss Treatments
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