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research A role for p75 neurotrophin receptor in the control of apoptosis‐driven hair follicle regression

96 citations , October 2000 in “The FASEB Journal”

In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.

research Epithelial growth control by neurotrophins: leads and lessons from the hair follicle

99 citations , January 2004 in “Progress in brain research”

This review examines the role of neurotrophins in hair follicle development and remodeling, highlighting potential therapeutic applications for hair growth disorders, but it reports no new empirical findings.

research HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy

January 2024 in “Theranostics”

This study found that HDAC6 plays a crucial role in regulating primordial follicle activation, with its overexpression delaying activation and preserving fertility by reducing NGF levels.

research Inhibitory Effects of Polyacetylene Compounds from Panax ginseng on Neurotrophin Receptor-Mediated Hair Growth

7 citations , January 2017 in “Biological & Pharmaceutical Bulletin”

This study found that polyacetylene compounds in Panax ginseng extracts may inhibit neurotrophin receptor binding, suggesting potential therapeutic benefits for alopecia and other hair growth disorders.

research Neuroimmunology of Stress: Skin Takes Center Stage

375 citations , July 2006 in “Journal of Investigative Dermatology”

This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.

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community Oral v topical Min & Dutasteride

16 upvotes 1 month ago

The user experienced hair loss after switching from topical to oral minoxidil and adding dutasteride, leading to doubts about its effectiveness. They are considering returning to RU58841 or topical minoxidil due to continued shedding and mental distress.

community Day 1 v 3 month progress. Topical Spray used in the UK.

68 upvotes 3 weeks ago

A user in the UK reports significant hair growth progress after three months using a topical spray containing Minoxidil, Finasteride, and Tretinoin, applied daily. They recommend the product from e-Surgery, noting no side effects and using Biotin shampoo every two days.

community Is 0.1%w/v topical fin overkill if taking oral 0.5mg fin?

in Finasteride/Dutasteride 2 upvotes 7 months ago

The conversation discusses whether using 0.1% topical finasteride alongside 0.5 mg oral finasteride is excessive, with suggestions to choose either oral or topical treatment. The user also uses 5% minoxidil and mentions concerns about alcohol-based solutions due to seborrheic dermatitis.

community Best reversing hairloss protocol i’v seen - do you trust it?

in Treatments 104 upvotes 1 year ago

The conversation discusses a hair loss protocol and compares it to using finasteride and minoxidil. It suggests that while the protocol includes some good advice, it may not surpass the effectiveness of established treatments like finasteride and minoxidil.

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