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    GlossaryType I Interferons

    proteins that help the immune system fight viral infections

    Type I Interferons (Type I IFNs) are a group of proteins that play a crucial role in the body's immune response to viral infections. They help to inhibit viral replication within host cells and activate immune cells, such as natural killer cells and macrophages, to fight off the infection. These proteins are also involved in regulating the immune system and can influence the development of autoimmune conditions.

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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

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      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

      in Finasteride/Dutasteride  123 upvotes 7 months ago
      The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

      community 3 years of 1 mg of Finasteride daily

      in Progress Pictures  867 upvotes 4 years ago
      A user who was able to regrow hair loss with 1mg of finasteride daily over 3 years, the effectiveness of finasteride for different races, and potential side effects associated with taking finasteride.