research Localization of mechanosensitive channel TRPV4 in mouse skin
In this study, TRPV4 channels were found in specific mechanosensory endings in mice skin, suggesting a role in pressure sensation transmitted through A- and C-fibers.
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5 / 202 resultsresearch TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro
TRPV4 slows hair growth by affecting hair follicle cells.
research Transient stimulation of TRPV4‐expressing keratinocytes promotes hair follicle regeneration in mice
This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.
research Cutaneous TRPV4 Potentiates the Afferent Transmission of Electroacupuncture Stimulation
In this study, calcium imaging in transgenic mice revealed that non-neuronal TRPV4 in the skin enhances afferent signaling during electrical stimulation, suggesting a role for neuroimmune interaction in acupuncture signal initiation.
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