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Did you mean Tropomyosin receptor kinase A?

GlossaryTropomyosin receptor kinase A

receptor protein involved in nerve growth and hair follicle health

Tropomyosin receptor kinase A (TrkA) is a protein that plays a crucial role in the development and function of the nervous system. It is a receptor for nerve growth factor (NGF), which is essential for the survival, growth, and maintenance of certain types of neurons. TrkA is also involved in pain perception and can influence hair growth by affecting the health of hair follicles.

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research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons

11 citations, December 2011 in “Biochemical journal”

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

research Pubertal Hormones Increase Hippocampal Expression of α4βδ GABAA Receptors

5 citations, February 2019 in “Neuroscience letters”

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Efficacy of Spironolactone as Adjunctive Therapy to Sodium Valproate in Bipolar-I Disorder: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial

research Efficacy of Spironolactone as Adjunctive Therapy to Sodium Valproate in Bipolar-I Disorder: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial

1 citations, November 2023 in “Brain and behavior”

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

research Eph Receptors and Ephrins: Therapeutic Opportunities

222 citations, October 2014 in “Annual Review of Pharmacology and Toxicology”

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

research Oral Administration of TrkB Agonist, 7,8-Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin-Induced Vestibular Injury in Guinea Pig

February 2023 in “Pharmaceutics”

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