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GlossaryTropomyosin receptor kinase A

receptor protein involved in nerve growth and hair follicle health

Tropomyosin receptor kinase A (TrkA) is a protein that plays a crucial role in the development and function of the nervous system. It is a receptor for nerve growth factor (NGF), which is essential for the survival, growth, and maintenance of certain types of neurons. TrkA is also involved in pain perception and can influence hair growth by affecting the health of hair follicles.

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research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons

11 citations, December 2011 in “Biochemical journal”

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

research Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature

40 citations, December 2016 in “Journal of Dermatological Treatment”

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

research Eph Receptors and Ephrins: Therapeutic Opportunities

222 citations, October 2014 in “Annual Review of Pharmacology and Toxicology”

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

research Pubertal Hormones Increase Hippocampal Expression of α4βδ GABAA Receptors

5 citations, February 2019 in “Neuroscience letters”

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

research Transcranial Photobiomodulation for Brain Diseases: Review of Animal and Human Studies Including Mechanisms and Emerging Trends

February 2024 in “Neurophotonics”

Light therapy on the brain shows promise for treating brain diseases and improving brain function.

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