This article discusses the impact of estrogens on skin aging, highlighting the potential benefits and unresolved effectiveness of alternatives like phytoestrogens and selective estrogen receptor modulators; it reports no new clinical results.
December 2025 in “International Journal of Innovative Technologies in Social Science”
This review suggests that while estrogen-targeted therapies may improve skin quality in postmenopausal women, systemic risks limit hormone replacement therapies, and more research is needed for localized treatments.
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December 2005 in “Experimental Dermatology”
This article discusses the role of estrogens in skin aging and reports no new findings; it highlights the potential of selective ER modulators to improve skin health without systemic side effects.
The post discusses a user's successful hair regrowth using finasteride, dutasteride, topical minoxidil, and estrogen over nine months. The user, who is male-to-female (mtf), reports significant regrowth and no side effects beyond typical hormone replacement therapy effects.
The user experienced significant hair regrowth and fullness after starting hormone replacement therapy (HRT) with sublingual estrogen and spironolactone, in addition to using a topical solution of minoxidil, finasteride, ketoconazole, and biotin. They noted initial shedding phases but emphasized that shedding is a sign of future growth.
A 26-year-old male considering a hair transplant is using topical finasteride and minoxidil, planning to start feminizing hormone replacement therapy (HRT) with estrogen and spironolactone. Many suggest waiting to see the effects of HRT, which may significantly regrow hair, before deciding on a transplant, and recommend adding microneedling and possibly switching to oral treatments for better results.
A 24-year-old male using topical finasteride for hair loss is experiencing thinning despite treatment and has high estrogen levels. He is seeking advice on whether high estrogen could be causing hair loss and how others with high estrogen levels have addressed it.
Significant hair regrowth was achieved using a topical combination of 0.3% finasteride and 6% minoxidil, with weekly dermastamping and ketoconazole shampoo, without side effects. Others suggested additional treatments like red light therapy and PRP.
Estrogen hormone, prescribed in tablet, patch and gel forms
How does topical Estradiol compare to oral Estradiol in treating alopecia?No study has compared topical and oral estradiol for hair loss, and estradiol applied to skin is still absorbed into the blood. Either form needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.
Alfatradiol: What does a form of estrogen have to do with hair loss in men?Alfatradiol (17α-estradiol) is a topical hormone sold without prescription in German pharmacies, licensed there for mild androgenetic alopecia, and not FDA-approved. The controlled trial evidence is in women, where hair density and thickness stayed nearly unchanged over 6 months while minoxidil improved them (the trial had no placebo group); no comparable placebo-controlled trial in men appears to have been published.