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research Clinical Efficacy of a Topical Compounded Formulation in Male Androgenetic Alopecia: Minoxidil 10%, Finasteride 0.1%, Biotin 0.2%, and Caffeine Citrate 0.05% Hydroalcoholic Solution.

1 citations , February 2020 in “PubMed”

This study found that a topical compounded formulation may improve hair density and general appearance in male patients with androgenetic alopecia after 6 months of use.

research Survey of the Prices of Topical Compounded Medications for Alopecia in the Tri-State Area.

March 2024 in “PubMed”

This survey study reported the pricing, formulation, and delivery options for compounded topical alopecia medications in the tri-state area, finding varied costs and noting the capability of most pharmacies to exceed commercially available minoxidil concentrations and offer delivery services.

research Compounded topical preparations in plaque psoriasis: Still a place for it in 2018?

1 citations , November 2018 in “Dermatologic Therapy”

This report describes the use of compounded topical preparations to treat two severe psoriasis patients and calls for further studies on their regulation, protocol, and stability evaluation.

Patient Satisfaction, Side Effects, And Other Reactions Reported By Adult Men Prescribed Compounded, Topical Finasteride Via A National Telehealth Platform: A Retrospective Analysis Of Real World Data

research Patient satisfaction, side effects, and other reactions reported by adult men prescribed compounded, topical finasteride via a national telehealth platform: A retrospective analysis of real world data (Preprint)

September 2025

In this large retrospective study, patients using compounded topical finasteride and minoxidil through a telehealth platform for male androgenetic alopecia reported high satisfaction and low incidence of side effects, with no need for higher care or treatment discontinuation due to adverse reactions.

research Efficacy and safety of compound glycyrrhizin combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials

2 citations , September 2024 in “Journal of Dermatological Treatment”

In this study, combining compound glycyrrhizin with topical minoxidil was more effective and as safe as minoxidil alone for treating alopecia areata.

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Community Join

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community Topical Dut Compound Journal (Strut Pharmacy) - Starting next week. Need YOUR feedback!

in Finasteride/Dutasteride 8 upvotes 5 years ago

The user, on testosterone replacement therapy, found finasteride and minoxidil ineffective for hair loss. They are trying a new topical gel with dutasteride, tretinoin, and a higher concentration of minoxidil, and plan to document the results.

community Topical 5% minoxidil vs compounded topical spray

3 upvotes 5 months ago

A user is considering switching from regular 5% minoxidil foam to a compounded 5% minoxidil spray with added caffeine, melatonin, and tretinoin for easier application and potentially better results. Another user mentions that tretinoin can enhance minoxidil's effectiveness by converting it to its active form.

community Does anyone compound their own fin topicals?

6 years ago

The conversation is about a person considering making their own topical finasteride to avoid side effects from oral use. They discuss potential methods and ingredients, including cayenne pepper extract, rosemary, and coconut oil, and seek advice on effectiveness and alternatives like light therapy or dermarolling.

community Is this fin/dut/min topical compound overkill?

4 upvotes 4 years ago

A user questions if a topical compound with finasteride, dutasteride, minoxidil, retinoic acid, caffeine, and triamcinolone is excessive for hair loss treatment. Another user shares their experience using topical finasteride without issues and notes that alternating finasteride and dutasteride is common.

community Where can I get this topical solution compounded?

in Treatment 1 upvotes 7 months ago

A user is seeking a pharmacy to compound a topical solution containing Minoxidil, Finasteride, Alfatradiol, Melatonin, Latanoprost, and either RU58841 or Pyrilutamide. They prefer a professional compounding lab over DIY methods.

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Learn

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learn TDM-105795

How is TDM-105795 used in hair-related products, and is it being explored as a topical treatment, an oral option, or both? TDM-105795 is not sold in any hair product — it is an unapproved experimental compound. The public trial registry shows it has been studied only as a topical scalp solution, in three completed company trials (the largest a 71-participant, 16-week Phase 2); no oral programme is registered, and no peer-reviewed publication exists.

learn Dutasteride

Dutasteride: What if I just want to grow back some hair without taking pills every day? There is no approved topical dutasteride; it exists only as pharmacy-compounded preparations and small studies, so its effectiveness and long-term safety are not established.

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn GHK-Cu

GHK-Cu: Does it have side effects or is it completely safe? For topical cosmetic use, the small laboratory evidence base found GHK-Cu non-irritating, and reported reactions are local and uncommon; for injected or oral use there is effectively no human safety data, and the FDA lists GHK-Cu among bulk substances that may present significant safety risks in compounding.

learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Do you want finasteride to penetrate better? The ideal solvent to maximize its effect. Formulation sources describe propylene glycol and microemulsion vehicles as increasing how much topical finasteride crosses the skin, but better penetration has not been shown to mean better hair results, and it also raises systemic exposure. The vehicle and strength are decisions for a prescriber or compounding pharmacist.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

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