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research Postmenopausal hormone replacement therapy and changes in skin connective tissue

January 2011 in “Zhongguo shiyong fuke yu chanke zazhi”

This study concludes that hormone therapy can significantly improve skin hydration, elasticity, thickness, and reduce wrinkles by modulating various skin cells through estrogen receptors.

research Menopause and Dermal White Adipose Tissue Depletion: Mechanistic Links, Adipogenesis, and Regenerative Therapeutic Replacement

January 2026 in “Journal of Cosmetic Dermatology”

This study reviewed evidence suggesting that the loss of dermal white adipose tissue (dWAT) during menopause may be linked to decreased estrogen levels, potentially affecting skin health, and discussed non-hormonal treatments, like magnolol, that might help restore dWAT and improve menopausal skin changes.

research MON-203 Dermatological Effects Of Hormone Replacement Therapy

October 2025 in “Journal of the Endocrine Society”

This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

research Activation and regulation of the granulation tissue derived cells with stemness-related properties

14 citations , April 2015 in “Stem Cell Research & Therapy”

This study found that dermal stem cells from granulation tissue promoted wound healing and reduced fibrosis in a combined radiation and skin wound mouse model.

research Tissue Engineering of the Reproductive System

1 citations , December 2010 in “Elsevier eBooks”

This review covers cell transplantation methods for genitourinary reconstruction, discussing tissue sources and complications but presenting no new clinical findings.

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Community Join

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community Dutasteride and TRT study indicates improvement in aging male symptoms and no difference between placebo group and dutasteride group

in Finasteride/Dutasteride 45 upvotes 1 month ago

Dutasteride is recommended for men on testosterone replacement therapy (TRT) with DHT-sensitive hair, as it does not interfere with TRT's anabolic effects and may improve libido and aging male symptoms. Users report varying experiences with libido when switching from finasteride to dutasteride, with some noticing improvements and others experiencing fluctuations.

community 11 months progress, HRT + Fin + Min

in Progress Pictures 366 upvotes 6 months ago

A transwoman shared her 11-month progress using hormone replacement therapy (HRT), finasteride, and minoxidil, reporting significant hair regrowth and satisfaction with the results. The discussion included various perspectives on HRT, its effects on hair and sexual function, and personal experiences with similar treatments.

community 4 month hair growth update on 1mg Fin and 5mg liquid minoxidil along with HRT

203 upvotes 1 week ago

The user shared a 4-month hair growth update using 1mg finasteride, 5mg liquid minoxidil, and hormone replacement therapy (HRT), reporting significant hair regrowth. They also use a derma stamp, scalp massages, and a DHT-blocking shampoo.

community My 2 Years Progress (Hair Recovery)

1465 upvotes 5 months ago

A person shared their hair regrowth journey using HIMS topical treatments with finasteride, minoxidil, hormone replacement therapy (HRT), and microneedling. They also discussed their transition as a transgender woman and the positive impact of HRT on hair recovery.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

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Learn

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learn Overview

learn Stem Cell Factor

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