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      learn Alfatradiol

      Weak form of estrogen applied to the scalp
      • Alfatradiol: Can it help if my hair loss is linked to DHT? The one randomised trial of topical alfatradiol — in 103 women — found hair thickness and density essentially unchanged after six months, while minoxidil improved both; its authors credited alfatradiol with slowing hair loss, but the trial had no placebo group to test that. Laboratory work on isolated follicles suggests a local effect on DHT, but no controlled trial in men appears to have been published.
      • Does Alfatradiol work the same for women, men, and trans people? Almost all controlled data on topical alfatradiol comes from cisgender women, where hair density and thickness stayed nearly unchanged over 6 months while minoxidil improved them (the trial had no placebo group). No published controlled trial covers cisgender men, and none covers trans people at all — so the honest answer is that the difference has not been measured.
      • How long should I wait to see if Alfatradiol is working for me? The one randomised trial and community reports both point to waiting at least 3 to 6 months. That trial, in about 100 women over six months with no placebo group, found no improvement in hair thickness or density; its authors credited alfatradiol with slowing hair loss.
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      learn Estradiol

      Estrogen hormone, prescribed in tablet, patch and gel forms