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Research

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research T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities

66 citations , March 2018 in “British journal of dermatology/British journal of dermatology, Supplement”

This article reviews the role of perifollicular regulatory T cells in maintaining hair follicle integrity in the context of hidradenitis suppurativa and calls attention to inflammatory mechanisms without reporting new clinical results.

research Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing

176 citations , August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.

research Anticytokine therapy, particularly anti-IFN-γ, in Th1-mediated autoimmune diseases

9 citations , May 2005 in “Expert Review of Clinical Immunology”

This article examines anticytokine therapies for autoimmune diseases, highlighting the potential of anti-interferon-γ as a universal treatment for certain conditions and noting varying effectiveness of tumor necrosis factor-α inhibitors.

research Inheritance-Specific Dysregulation of Th1- and Th17-Associated Cytokines in Alopecia Areata

1 citations , August 2023 in “Biomolecules”

This study found that patients with alopecia areata and their healthy family members had elevated levels of Th1- and Th17-related cytokines, suggesting a genetic link in cytokine dysregulation.

research The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications

37 citations , December 2021 in “Cells”

This study found that dysregulation of systemic Th1, Th2, and Th17 cytokines is associated with alopecia areata, with specific cytokines linked to disease activity and treatment response.

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Community Join

5 / 39 results

community Has Anyone Gotten Results With TH16?

4 upvotes 3 years ago

The conversation discusses using TH16, a topical melatonin with resveratrol, and stemoxydine for hair maintenance, avoiding finasteride and minoxidil due to side effects. The user is considering a low-dose topical finasteride despite sensitivity.

community 26 male 1 year 9 month therapy (fin,min,dut, micro needling)

440 upvotes 1 year ago

A 26-year-old male shared his hair loss treatment journey using finasteride, minoxidil, dutasteride, and microneedling, noting dissatisfaction with hair thickness but hoping for improvement. Users discussed side effects, treatment effectiveness, and shared personal experiences with similar treatments.

community Switched from dut to fin for 1.5 months then back dut now hairline is nuked

120 upvotes 1 year ago

Switching from dutasteride to finasteride and back led to significant hair shedding, despite continued use of oral minoxidil. The user is hopeful for hair regrowth after resuming dutasteride.

community high estrogen levels after 10month fin

9 upvotes 3 years ago

A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

community Where to buy Latanaprost or equivalent?

2 upvotes 1 year ago

The conversation discusses using Latanoprost for hair regrowth, with the original poster seeking advice on where to purchase it without a prescription. Users suggest alternatives like Triple Hair's TH-07, which includes Finasteride, Minoxidil, and Latanoprost, and Strut's Latanoprost with melatonin and caffeine.

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Experts

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Clinics

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Learn

1 / 800 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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