March 2026 in “Seven Editora eBooks” This systematic review evaluates the composition, mechanisms, efficacy, safety, and risks of topical testosterone formulations, such as creams, gels, ointments, and transdermal patches, used primarily by middle-aged and elderly men. The review, covering studies from 2010 to 2025, finds that while testosterone creams have variable absorption, gels provide stable bioavailability, and patches ensure continuous release. Despite their effectiveness in increasing serum testosterone levels, these formulations can lead to adverse effects like acne, gynecomastia, alopecia, and potential stimulation of prostate or breast cells. The study concludes that due to significant systemic risks, these products should only be used under strict medical supervision.
9 citations
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May 2008 in “Journal of Clinical Oncology” A woman's ovarian tumor causing high testosterone was successfully removed, and her symptoms improved.
305 citations
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February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
165 citations
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February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
19 citations
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May 2020 in “American journal of men's health” Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.