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Glossary Testosterone

hormone that regulates male traits and reproductive functions

Testosterone is a hormone primarily produced in the testes in men and in smaller amounts in the ovaries and adrenal glands in women. It plays a crucial role in the development of male reproductive tissues, the promotion of secondary sexual characteristics like increased muscle and bone mass, and the growth of body hair. Additionally, testosterone influences mood, energy levels, and overall well-being.

Related Terms

Research

5 / 1000+ results

New Progesterone Esters as 5α-Reductase Inhibitors

research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.

22 citations , January 2001 in “Chemical & Pharmaceutical Bulletin”

This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.

research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors

13 citations , January 2005 in “Chemical and Pharmaceutical Bulletin”

This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.

Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS

8 citations , July 2018 in “Analytical sciences”

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

research Studies on the efficacy of methyl esters of n-alkyl fatty acids as penetration enhancers

3 citations , September 1989 in “Journal of Investigative Dermatology”

This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.

research The Antiandrogenic Action of 4–Androsten–3–one–17β– Carboxylic Acid and Its Methyl Ester on Hamster Flank Organ1

87 citations , April 1973 in “Endocrinology”

This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.

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Community Join

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community DIY Testosterone replacement therapy and fin

15 upvotes 3 months ago

An 18-year-old is considering testosterone replacement therapy with finasteride or dutasteride for hair loss but worries about side effects. Users recommend alternatives like minoxidil, RU58841, and consulting a doctor.

community 2.5mg Dut/RU/minoxidil can't counter 15mg Testosterone..

in Finasteride/Dutasteride 6 upvotes 1 year ago

Despite using Dutasteride, RU58841, and Minoxidil, hair loss continues due to low testosterone levels from taking 15mg of testosterone weekly, which may not produce enough estrogen. Increasing testosterone dosage and stabilizing hormone levels might help address the issue.

community Female on DHT blockers, need some advice.

5 upvotes 11 months ago

A female experiencing hair loss while on testosterone replacement therapy is using oral Minoxidil, Spironolactone, and finasteride, but still losing hair. Suggestions include switching to dutasteride, using topical anti-androgens, and reducing Nizoral shampoo use to prevent scalp dryness.

community Whey Protein can cause hairloss in men with AGA as per a doctor

64 upvotes 8 months ago

Whey protein may slightly increase hair loss in men with androgenetic alopecia (AGA) due to elevated IGF-1 and testosterone levels, but the effect is minimal compared to treatments like finasteride and dutasteride. Many users argue that whey protein's impact on hair loss is negligible and that maintaining a healthy lifestyle is more important.

community Two years on dutasteride and minoxidil

293 upvotes 1 year ago

The conversation discusses a user's two-year experience using oral dutasteride and minoxidil for hair loss, noting initial gains and stabilization over time, with some concerns about shedding and a weak spot at the crown. The user also mentions using testosterone cypionate and reports no significant side effects, except possibly dry eyes.

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Learn

2 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Bicalutamide

Could bicalutamide help trans women regrow hair lost to testosterone? No study has tested bicalutamide for hair regrowth in trans women. In cisgender women the only randomized trial found it added nothing to minoxidil, and it is an off-label prescription drug that requires liver monitoring.

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