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research A review of acitretin, a systemic retinoid for the treatment of psoriasis

75 citations , August 2005 in “Expert Opinion on Pharmacotherapy”

This review discusses the use of acitretin, a retinoid approved since 1997, for various forms of psoriasis and its potential benefits in combination therapy, but reports no new clinical findings.

research Systemic Lupus Erythematosus

37 citations , January 1979 in “Archives of Dermatology”

This case report suggests that PUVA treatment may have played a role in triggering systemic lupus erythematosus in a 23-year-old woman with psoriasis.

research 015 Hypopigmented Mycosis Fungoides Progressing to Systemic Involvement- A Case Report and Review of Literature

September 2017 in “Journal of Investigative Dermatology Symposium Proceedings”

This review discusses the clinical features of hypopigmented mycosis fungoides in primary cutaneous T cell lymphoma and reports no new clinical results.

research Alopecia areata: diagnosis and management

48 citations , May 1999 in “International Journal of Dermatology”

This article reviews the diagnosis and management of alopecia areata but reports no new research findings.

research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women

7 citations , September 2013 in “Current Dermatology Reports”

This review summarizes existing literature on the safety of commonly used dermatologic medications during pregnancy but does not present new clinical findings, aiming to assist physicians with prescribing decisions.

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community Non-systemic hair loss stack, is there any hope?

6 upvotes 2 weeks ago

A 19-year-old is experiencing hair thinning and has tried various doses of oral and topical finasteride but faced psychological and sexual side effects. They are considering topical anti-androgens like KX826, ketoconazole cream, and RU58841 as alternatives, while others suggest clascoterone and topical dutasteride.

community Minimizing systemic DHT reduction with topicals

5 upvotes 3 weeks ago

The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

community How systemic can Ru58841 go?

2 upvotes 5 years ago

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Any treatment not nuking systemic DHT levels?

16 upvotes 6 months ago

Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.

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Learn

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learn Follistatin

Can follistatin be applied topically, or is it only effective through injections or systemic use? Follistatin is not effective when applied topically and requires injections or systemic use.

learn Thymosin Beta 4

Is Thymosin Beta 4 being explored more as a topical treatment or as a systemic (oral or injectable) approach for hair loss? Thymosin Beta 4 is primarily being explored as a topical treatment for hair loss.

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