A Review of Acitretin, a Systemic Retinoid for the Treatment of Psoriasis
August 2005
in “
Expert Opinion on Pharmacotherapy
”
TLDR Acitretin is effective for certain types of psoriasis, safe for long-term use, and often combined with other treatments.
The document reviewed the use of acitretin, a systemic retinoid, for treating psoriasis. It discussed the drug's efficacy, safety profile, and side effects. Acitretin was found to be effective in reducing psoriasis symptoms, but it had notable side effects, including mucocutaneous effects, elevated liver enzymes, and lipid abnormalities. The review emphasized the importance of monitoring patients closely during treatment and highlighted the need for further research to optimize dosing and minimize adverse effects.