A Review of Acitretin, a Systemic Retinoid for the Treatment of Psoriasis

    Chai Sue Lee, John Koo
    Studysummary This review discusses the use of acitretin, a retinoid approved since 1997, for various forms of psoriasis and its potential benefits in combination therapy, but reports no new clinical findings. Our plain-language summary of this paper — not a Tressless recommendation.
    The document reviewed the use of acitretin, a systemic retinoid, for treating psoriasis. It discussed the drug's efficacy, safety profile, and side effects. Acitretin was found to be effective in reducing psoriasis symptoms, but it had notable side effects, including mucocutaneous effects, elevated liver enzymes, and lipid abnormalities. The review emphasized the importance of monitoring patients closely during treatment and highlighted the need for further research to optimize dosing and minimize adverse effects.
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