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research TOTAL SYNTHESIS OF THE ACTIVE INGREDIENT ACETYL TETRAPEPTIDE-3 FOR HAIR LOSS TREATMENT AND SCALP CARE

March 2025 in “Journal of Science Natural Science”

This study successfully synthesized acetyl tetrapeptide-3 on a laboratory scale with over 56% yield and 100% purity, supporting its use in developing hair loss and scalp care products.

research Herbal Shampoo Bar as a Sustainable Alternative to Synthetic Hair Cleanser: A Review

October 2025 in “International Journal of Research and Review”

This study highlights the potential benefits of herbal soaps and shampoo bars as eco-friendly alternatives to conventional cosmetics, noting their antibacterial, antifungal, and antioxidant properties as well as sustainability advantages such as reduced plastic use and avoidance of synthetic chemicals.

research Development and Physicochemical Evaluation of Polyherbal Dry Powder Shampoo Using Natural Ingredients for Healthy Hair

April 2026 in “International Journal of Drug Delivery Technology”

In this study, researchers developed and tested a polyherbal dry powder shampoo using natural ingredients like Neem and Aloe vera, reporting good foaming ability, appropriate pH, no skin irritation, and stability, suggesting it as a safe and affordable alternative to synthetic shampoos.

research Plant cell culture as emerging technology for production of active cosmetic ingredients

67 citations , June 2018 in “Engineering in Life Sciences”

This review discusses advancements in plant cell culture technology for producing potent natural cosmetic ingredients and reports no new experimental results.

research Regulatory Mechanisms of Natural Active Ingredients and Compounds on Keratinocytes and Fibroblasts in Mitigating Skin Photoaging

10 citations , August 2024 in “Clinical Cosmetic and Investigational Dermatology”

This review reports that natural compounds show promise in slowing skin photoaging by targeting cellular pathways in keratinocytes and fibroblasts. However, comprehensive clinical studies are needed to verify their efficacy and safety.

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Learn

5 / 11 results

learn sh-Polypeptide-7

Is sh-Polypeptide-7 considered a natural or synthetic ingredient, and how is it typically applied? sh-Polypeptide-7 is a synthetic (lab-made) form of human growth hormone, used in some topical skin and hair-care products. There is no published human trial showing that it benefits hair, and its safety on the scalp has not been studied.

learn Hydrocortisone

Mild corticosteroid used on the skin and scalp

learn Stem Cell Factor

learn Thymosin Beta 4

learn Glycerin

What’s the difference between vegetable glycerin and synthetic glycerin in hair products? Vegetable glycerin is plant-derived, while synthetic glycerin is petroleum-based, but both are chemically identical.

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Community Join

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community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

89 upvotes 10 months ago

The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

community Organic Self Tanner on bald Scalp?

1 upvotes 3 years ago

The user is using topical minoxidil and finasteride, along with daily derma rolling, and is considering using an organic self-tanner on their shaved scalp. They seek advice on whether the self-tanner's ingredients could harm hair regrowth.

community VDPHL-01 is Overrated and Ridiculous. This is just Oral Minoxidil.

in Research/Science 21 upvotes 1 year ago

VDPHL-01 is essentially a slow-release oral minoxidil, which is already known to work for hair growth. The formulation includes other ingredients like Medrogestone, Valproic acid, Setipiprant, and Cetirizine, but their effectiveness and necessity are questioned.

community Topical solution recommendation

in Treatment 2 upvotes 1 year ago

The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

community Topical solution recommendation

in Product 1 upvotes 1 year ago

The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

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