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Glossary Cell Surface Receptors

specialized proteins on cell membranes that receive external signals

Cell Surface Receptors, also known as Cell Membrane Receptors or Plasma Membrane Receptors, are specialized proteins located on the surface of cells. They act like antennae, receiving signals from outside the cell—such as hormones, neurotransmitters, or growth factors—and transmitting these signals into the cell to trigger a specific response. This process is crucial for various cellular functions, including growth, immune responses, and communication between cells.

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Research

5 / 1000+ results

research Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate in Arabidopsis thaliana

44 citations , January 2023 in “New Phytologist”

This study found that low temperature triggers root hair elongation in Arabidopsis thaliana through a FERONIA-ROP2-TORC signaling pathway, also activated by nitrogen deficiency.

Cell Surface Receptor Kinase FERONIA Linked to Nutrient Sensor TORC Signaling Controls Root Hair Growth at Low Temperature Linked to Low Nitrate in Arabidopsis Thaliana

research Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate inArabidopsis thaliana

2 citations , January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.

research Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate

1 citations , June 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

This study found that deleting the vitamin D receptor from specific stem cells in mouse hair follicles disrupts their ability to regenerate the epidermis after injury, suggesting an essential interaction with the transcription factor p63.

research 1361 A novel cell surface marker for hair follicle dermal cells throughout hair morphogenesis and cycling

April 2018 in “Journal of Investigative Dermatology”

This study suggests that the Leptin receptor may serve as a novel cell surface marker for dermal papilla cells, potentially aiding future isolation and research efforts in hair follicle regeneration studies.

research The epidermis: rising to the surface

238 citations , October 1994 in “Current opinion in genetics & development”

This article reviews the role of epidermal proteins and regulatory mechanisms in skin diseases, emphasizing recent insights but reports no new experimental results.

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Community Join

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community How can ketoconazole shampoo block androgen receptor if it's just washed off?

60 upvotes 10 months ago

Ketoconazole shampoo is primarily used to reduce scalp fungus and inflammation, not to block DHT or androgen receptors. It may help with seborrheic dermatitis and improve scalp health, but its effects on hair loss are minimal compared to treatments like finasteride.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 1 month ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community GT20029 and PP405 the new fin and min that we been waiting for ?

36 upvotes 1 year ago

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

community 2 months of nightly 5% minoxidil

in Progress Pictures 485 upvotes 7 months ago

A 25-year-old user shared progress after two months of using 5% minoxidil nightly on their scalp and beard. Many users suggest combining minoxidil with finasteride or dutasteride to prevent hair loss due to DHT, while others express concerns about potential side effects of these DHT blockers.

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