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Glossary Stromal Cells

connective tissue cells supporting organ structure and function

Stromal cells are a type of connective tissue cell found in various organs, including the skin, bone marrow, and fat. They provide structural support and secrete factors that help regulate the function and growth of nearby cells, including those involved in hair growth and repair. For professionals, stromal cells are crucial in tissue engineering and regenerative medicine due to their role in creating a supportive microenvironment for tissue regeneration.

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Research

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research The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair

295 citations , June 2009 in “Science”

This article reviews the role of stromal stem cells in mammalian wound repair, suggesting they may perform functions similar to blastemal cells in simpler organisms, but reports no new experimental results.

research Mesothelial Stem Cells and Stromal Vascular Fraction for Skin Rejuvenation

11 citations , August 2018 in “Facial Plastic Surgery Clinics of North America”

This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.

research Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss

13 citations , August 2018 in “Facial Plastic Surgery Clinics of North America”

This review discusses the potential effectiveness of cell therapy for hair loss, highlighting promising early findings but emphasizing that more research is needed to explore specific therapies like autologous fat grafting and mesenchymal stem cells.

research Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy

16 citations , January 2024 in “World Journal of Stem Cells”

This review highlights the need for optimizing mesenchymal stromal/stem cell therapy through tailored in vitro strategies to unlock their full potential for treating specific diseases.

research Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints

8 citations , October 2021 in “Stem Cell Research & Therapy”

This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.

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community Conversation with 3-4 top dermatologists - no consensus

5 upvotes 4 months ago

Dermatologists have differing opinions on hair loss treatments, with some using topical dutasteride, oral minoxidil, exosome therapy, PRP, and various other therapies. The user plans to use a topical solution of dutasteride, minoxidil, tretinoin, PRP, and LLLT.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 7 upvotes 2 years ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Stem-cell hair transplants! 20k lab grown grafts from one single graft

50 upvotes 2 years ago

Stem-cell hair transplants could potentially create thousands of grafts from a single donor graft, offering a solution for hair loss with DHT-resistant hair. Companies like Stemson Therapeutics and OrganTech are working on this technology, which may become available in the future, possibly reducing the cost and making it widely accessible.

community Anyone heard of HairStemCell Transplant? They claim not needing to pull the entire hair cell, allowing reuse of same donor area.

4 upvotes 8 years ago

HairStemCell Transplant claims to reuse the donor area without removing the entire hair cell, but results in finer hair that may not regrow after cycles. The technique is costly and less effective than traditional transplants for full coverage.

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