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research The profile of steroid hormones in human fetal and adult ovaries

11 citations , May 2024 in “Reproductive Biology and Endocrinology”

In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.

research Investigation Into the Metabolism and Elimination Behavior of RU 58841, and Its Influence on the Steroid Profile in Humans

August 2026 in “Biomedical Chromatography”

This study found that topical application of RU 58841 resulted in considerable systemic exposure, identifying several metabolites without affecting steroid profile determinations in routine doping controls.

research HPLC Profiling and Insilco studies of Chochurus olitoris (Jute) Leave Fractions against Steroid 5α-Reductase 2 (SRD5α2)

August 2024 in “Biomedical Journal of Scientific & Technical Research”

This review discusses the role of steroid 5 alpha reductase 2 in converting testosterone to DHT and its association with conditions like benign prostatic hyperplasia and prostate cancer; it reports no new results.

research LC‐MS/MS‐based method for long‐term steroid profiling in human scalp hair

134 citations , March 2015 in “Clinical Endocrinology”

This study introduced a validated LC-MS/MS-based method for profiling long-term steroid concentrations in human scalp hair, offering potential applications in endocrinology research.

research Gas chromatography/mass spectrometry based hair steroid profiling may reveal pathogenesis in hair follicles of the scalp

30 citations , April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry”

This study found that using hair steroid profiling, dutasteride treatment led to reduced dihydrotestosterone levels and DHT/testosterone ratio in patients with male-pattern baldness.

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Community Join

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community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community Very agressive protection / regrowth stack on steroids

in Journals / Progress Pictures 223 upvotes 8 months ago

A 24-year-old with hair thinning is using a regimen including dutasteride, RU58841, HGH, GHK-cu, and other compounds to protect and regrow hair. They are also incorporating a mild cutting cycle with testosterone propionate, anavar, and tirzepatide.

community How to Keep Your Hair on Steroids

25 upvotes 2 years ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community Why Fin/Dut Isn't Working for You GPR133: a new hairloss mechanism + Steroid Hair Loss Deep Dive

6 upvotes 2 months ago

Hair loss may be linked to the GPR133 receptor, independent of the androgen receptor pathway. Treatments like finasteride, dutasteride, minoxidil, RU58841, and KX-826 show varying results, with hair loss persisting due to high testosterone and GPR133's role.

community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?

in Finasteride/Dutasteride 51 upvotes 1 year ago

Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.

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Learn

4 / 800 results

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn plant sterol complex

learn Hydrocortisone

Can hydrocortisone be used together with other treatments like minoxidil or steroid injections? Clinicians do use a mild steroid cream to settle the scalp irritation minoxidil can cause, but no verified trial tests hydrocortisone added to minoxidil or to corticosteroid injections, and prolonged scalp use risks skin thinning — combining it is a decision to take with a prescriber.

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Clinics

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