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    Did you mean Squamous Cell Carcinoma?
    Glossary Squamous Cell Carcinoma

    type of skin cancer originating in outer epidermal cells

    Squamous Cell Carcinoma (SCC) is a type of skin cancer that originates in the squamous cells, which are flat cells located in the outer part of the epidermis. It often appears as a red, scaly patch, open sore, or wart-like growth that may crust or bleed. While it can be aggressive and spread to other parts of the body if not treated, it is generally curable when detected early.

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    1. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin Nature communications · 2019 · 36 citations
    2. Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis American Journal Of Pathology · 2006 · 100 citations
    3. Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶ Photochemistry and Photobiology · 2005 · 28 citations
    4. Bilateral Squamous Cell Carcinoma of the Forehead 2020
    5. Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas Publisher · 2019
    6. The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells Pharmaceuticals · 2021 · 48 citations
    7. Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas Genes & Diseases · 2019 · 31 citations
    8. Aggressive Squamous Carcinomas of the Scalp Dermatologic Surgery · 2006 · 18 citations
    9. No Evidence That Human Papillomavirus Is Responsible for the Aggressive Nature of Recessive Dystrophic Epidermolysis Bullosa–Associated Squamous Cell Carcinoma Journal of Investigative Dermatology · 2010 · 14 citations
    10. RSPO1-mutated keratinocytes from palmoplantar keratoderma display impaired differentiation, alteration of cell–cell adhesion, EMT-like phenotype and invasiveness properties: implications for squamous cell carcinoma susceptibility in patients with 46XX disorder of sexual development Orphanet journal of rare diseases · 2022 · 5 citations
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