October 2020 in “Journal of Pharmaceutical Sciences” Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
Perilla seed extract may help prevent hair loss better than some standard treatments.
23 citations
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January 2018 in “Elsevier eBooks” Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.
1 citations
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January 2020 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This thesis explored the challenges of delivering drugs through the skin's stratum corneum (SC) barrier using nanoparticle (NP)-based systems and solvents. It investigated how SC barrier disruption, using tape stripping (TS) or cyanoacrylate stripping (CS), affected drug permeability, finding that skin permeability increased with SC reduction. A pH-sensitive Eudragit® L100 NP showed promise for targeted drug release, particularly in barrier-disrupted skin, which could simulate atopic dermatitis (AD) conditions. The study also examined solvent effects, finding that a cosolvent of ethanol and PBS enhanced drug penetration into viable skin layers more effectively than ethanol alone. Overall, the research provided insights into SC barrier disruption, NP drug delivery, and solvent effects, offering potential strategies for improving cutaneous drug delivery and reducing side effects in AD treatment.
39 citations
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April 2011 in “Recent Patents on Drug Delivery & Formulation” Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.