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Research

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research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

In this study, WNT10A was identified as a key gene in the development and maturation of skin hair follicles in fetal Inner Mongolian cashmere goats.

research Non-invasive monitoring of low molecular weight biomarkers relevant to skin inflammation and cancer

1 citations , January 2021

This study explored non-invasive methods for monitoring low molecular weight biomarkers on the skin's surface, concluding that certain amino acid ratios, such as Phe/Trp, could serve as potential indicators of skin inflammation and cancer.

research Skin Improvement Efficacy of Microspicule Cosmetics Containing Low-molecular-weight Peptide Complexes

March 2025 in “Asian Journal of Beauty and Cosmetology”

This study found that microspicule cosmetics with low-molecular-weight peptide complexes significantly improved skin whitening, pore condition, and skin barrier function over four weeks compared to a non-microspicule formulation.

research Skin manifestations and biophysical changes following weight reduction induced by bariatric surgery: A 2‐year prospective study

September 2023 in “The Journal of Dermatology”

In this 2-year prospective study, researchers observed that weight loss through bariatric surgery in patients with morbid obesity led to improvements in various skin conditions, although it also resulted in hair loss (telogen effluvium) for over half of the participants.

research 393 Skin manifestations and biophysical properties in patients with morbid obesity and changes after weight loss: A two-year prospective study

April 2023 in “Journal of Investigative Dermatology”

In this study, bariatric surgery in patients with morbid obesity improved various skin conditions, although acute telogen effluvium was common, with notable reductions in facial sebum and skin elasticity changes.

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Community Join

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community Did Dutasteride change how you look physically? your facial profile such as skin thickness, fat distribution or softness?

in Finasteride/Dutasteride 51 upvotes 1 year ago

Dutasteride and finasteride can cause changes in physical appearance, like more feminine features and increased water retention. Users report side effects such as reduced libido, weight gain, and improved skin clarity, while some notice no significant changes.

community Any men here taking oral spironolactone?

5 upvotes 2 months ago

Men discussing the use of oral spironolactone for androgenetic alopecia, with some reporting no immediate changes in hair but noticing clearer skin and weight loss. Concerns about side effects like gynecomastia and erectile dysfunction are mentioned, with users planning to adjust doses over time.

community Weight loss drugs linked to increased risk of hair loss, researchers say

in Research/Science 270 upvotes 2 months ago

Weight loss drugs may increase the risk of hair loss, but this is often temporary and influenced by genetics. Treatments like finasteride, minoxidil, and RU58841 are mentioned, with varying effectiveness depending on individual genetic sensitivity to DHT.

community Will minoxidil cause your skin to age from the collagen inhibition?

2 upvotes 7 months ago

Minoxidil is unlikely to cause skin aging at typical doses, and concerns about collagen inhibition are mostly unfounded. Users suggest using sunscreen and tretinoin for skin health, and some combine minoxidil with finasteride for hair maintenance.

community [26M] Min 5 month progress, worse skin?

49 upvotes 2 years ago

A user experienced skin irritation and acne while using Minoxidil foam, but after stopping both the foam and a sea salt spray, their skin improved. They plan to try oral Minoxidil, suspecting the sea salt spray, not Minoxidil, was the main cause of their skin issues.

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Clinics

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Learn

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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn Finasteride

Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid improved hydration of facial skin in trials. It has not been tested on the scalp.

learn Osteopontin

What does osteopontin do in skin healing and inflammation? Osteopontin takes part in wound repair in mouse skin; its role in human scalp healing and inflammation has not been studied.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Providers say SMP pigment can be matched to many skin tones and hair colors; claims that it works on all of them are marketing.

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Experts

1 / 3 results

SMP Specialist
Noelle Skin
Nice, France

Noelle Skin