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Glossary Skin Ulcers

open sores on skin that don't heal properly

Skin ulcers, also known as cutaneous ulcers or dermal ulcers, are open sores on the skin that fail to heal properly and can become chronic. They often result from poor blood circulation, prolonged pressure, or underlying medical conditions such as diabetes or vascular diseases. These ulcers can be painful, prone to infection, and may require medical intervention to promote healing and prevent complications.

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Research

5 / 1000+ results

research Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence‐based medicine

56 citations , March 2016 in “International Wound Journal”

This review concludes that autologous split-thickness skin grafting remains the gold standard for safety and efficacy in treating chronic leg ulcers, with greater success in venous ulcers.

research Skin microbiota and diabetic foot ulcers

6 citations , July 2025 in “Frontiers in Microbiology”

This study observed that in patients with diabetic foot ulcers, an imbalance in skin microbiota, with increased pathogenic bacteria, contributes to infection and poor wound healing, and suggests that modulating microbiota composition might improve healing outcomes.

research Hair-follicle transplant as chronic skin ulcer treatment

May 2022 in “Portuguese Journal of Dermatology and Venereology”

In this study, a case of chronic skin ulcer due to livedoid vasculopathy fully healed following hair-follicle transplantation, suggesting potential effectiveness of this treatment approach.

research Hair follicle transplantation promotes skin ulcer healing in a mouse model of experimental diabetes

August 2025 in “Scientific Reports”

This study found that hair follicle transplantation improved wound healing in diabetic mice by promoting tissue regeneration and reducing inflammation, with follicles from normoglycemic conditions proving more effective than those from hyperglycemic environments.

research Exercise in dermatology: Exercise’s influence on skin aging, skin cancer, psoriasis, venous ulcers, and androgenetic alopecia

2 citations , August 2021 in “Journal of The American Academy of Dermatology”

In this study, researchers reviewed the literature on the preventive and therapeutic roles of exercise in various skin diseases and assessed whether there are sufficient data to recommend exercise for each condition.

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Community Join

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community microneedle, any long term users damage?

in Microneedling 35 upvotes 2 years ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community 23M – 107 days on dutasteride (0.5mg/day) + minoxidil. Any real progress or too early?

in Is this regrowth? 116 upvotes 9 months ago

A 23-year-old male has been using dutasteride (0.5mg daily) and minoxidil with tretinoin for 107 days to address crown hair loss, noticing slight thickening but uncertain progress. He reports no shedding or side effects, experiencing positive effects like improved skin texture and increased energy.

community Anyone here who stopped microneedling and maintained or lost the gains?

in Microneedling 9 upvotes 1 year ago

Microneedling's long-term effects on hair loss are uncertain, with concerns about scarring and the need for continued use of minoxidil and finasteride to maintain gains. Finasteride does not sustain minoxidil-regrown hair without ongoing minoxidil use, and microneedling alone shows limited evidence of effectiveness.

community It's always the Mice that gets to grow back hair.

434 upvotes 10 months ago

Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

community Y'all, we have got to come to a consensus on the specifics of microneedling.

27 upvotes 4 years ago

Microneedling can promote hair growth, but there is uncertainty about the best practices, including needle length, device, and session frequency. Users discuss using needle lengths between 0.5mm and 1.5mm, with some experiencing pinpoint bleeding, and emphasize the need for more reliable resources and guidelines.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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