October 2023 in “International Journal of Cosmetic Science”
In this study, researchers developed WS Biotin, a new water-soluble form of biotin, and found that it significantly improves water solubility compared to free biotin and enhances hair-related keratin expression, gene activity for hair growth in vitro, while also reducing melanin content in skin cells.
34 citations
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November 2023 in “Applied Materials Today”
This review discusses the potential of topical nanoemulsions to transform skin cancer treatment by improving drug delivery and minimizing side effects, highlighting their advantages like enhanced skin permeation and controlled release, despite existing challenges.
This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.
7 citations
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December 2020 in “ACS biomaterials science & engineering”
In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.
A user asked if olive oil can replace propylene glycol or glycerin in topical finasteride preparation. Another user advised against it, suggesting MCT oil instead due to olive oil's potential to worsen dandruff and seborrheic dermatitis.
RU58841 is more effective when mixed with isopropyl alcohol instead of minoxidil, as water in minoxidil degrades RU58841. Applying RU58841 separately from minoxidil, with an hour gap, enhances hair growth results.
A serum with oleic and palmitoleic acids shows promise for hair regrowth in mice, but its effectiveness in humans is unproven. Minoxidil and finasteride remain the recommended treatments.
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.
ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.
Is scalp micropigmentation suitable for people with sensitive skin?Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.