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research 588 Skin fibroblast heterogeneity and plasticity are determined by the local niche

September 2019 in “Journal of Investigative Dermatology”

This study suggests that human skin contains distinct fibroblast subsets with unique expression profiles and functions, which can be isolated to investigate their role in skin pathogenesis.

research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer

211 citations , May 2018 in “Trends in cell biology”

This review explores recent insights into the diverse cell populations involved in skin development, homeostasis, wound healing, and cancer progression but reports no new results.

research Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments

137 citations , April 2015 in “Nature Reviews Molecular Cell Biology”

This review discusses the distinct roles and surprising developmental flexibility of multiple somatic stem cell types in tissue maintenance and repair, reporting no new results but highlighting emerging questions about their regulation and origins.

research 520 Body site heterogeneity and microbial diversity is lost in individuals with hidradenitis suppurativa

1 citations , April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study observed significant differences in the skin microbiome between hidradenitis suppurativa patients and healthy individuals, notably with decreased β-diversity and a distinct abundance of certain bacteria in affected skin.

research Stem Cell Heterogeneity and Plasticity in Epithelia

129 citations , May 2015 in “Cell Stem Cell”

This review discusses recent findings on the plasticity and regulation of epithelial stem cells and reports no new experimental results.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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Community Join

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community Nice product I discovered, thought I would share.

in Treatment 456 upvotes 1 year ago

A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

community [26M] Min 5 month progress, worse skin?

49 upvotes 2 years ago

A user experienced skin irritation and acne while using Minoxidil foam, but after stopping both the foam and a sea salt spray, their skin improved. They plan to try oral Minoxidil, suspecting the sea salt spray, not Minoxidil, was the main cause of their skin issues.

community Minoxidil inhibits lysyl hydroxylase which is needed to produce collagen. If I take 2,5...5 mg of minoxidil every day can I cause my skin to age prematurely?

32 upvotes 1 year ago

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

community Dutasteride is working very fast

6 upvotes 6 days ago

Dutasteride is causing rapid changes in skin oiliness, leading to a switch in skincare routine. Users discuss its effects on hair and skin, with some experiencing drier hair.

community Topical Finasteride that doesn’t go systematic is the cure

3 upvotes 1 year ago

Topical finasteride that doesn't penetrate the skin could potentially treat hair loss without side effects. Current challenges include finding a formulation that remains on the scalp without increasing blood levels.

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