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Did you mean Chronic Inflammatory Skin Condition?

Glossary Chronic Inflammatory Skin Condition

long-lasting skin disorder with persistent redness and swelling

A chronic inflammatory skin condition is a long-lasting disorder where the skin becomes red, swollen, and irritated due to an ongoing inflammatory response. Examples include psoriasis, eczema, and rosacea, where the immune system mistakenly attacks healthy skin cells, leading to symptoms like itching, scaling, and discomfort.

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Research

5 / 1000+ results

research LB943 Tofacitinib treatment of inflammatory skin conditions in patients with Down Syndrome

1 citations , July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.

research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions

January 2018 in “Springer eBooks”

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Evidence of a Causal Relationship Between Body Mass Index and Immune-Mediated and Inflammatory Skin Diseases and Biomarkers: A Mendelian Randomization Study

research Evidence of a Causal Relationship Between Body Mass Index and Immune-Mediated and Inflammatory Skin Diseases and Biomarkers: A Mendelian Randomization Study

2 citations , November 2024 in “Clinical Cosmetic and Investigational Dermatology”

This Mendelian randomization study suggests a causal link between higher BMI and increased risk of psoriasis, atopic dermatitis, and hidradenitis suppurativa, potentially due to elevated biomarkers such as triglycerides and C-reactive protein.

research Skin Microbiome Shifts in Various Dermatological Conditions

August 2025 in “Journal of Clinical Medicine”

This review found that in various dermatological diseases, skin microbiome diversity decreases, with an increased presence of pro-inflammatory strains, and suggests potential of prebiotic treatments as safer alternatives to antibiotics, though further research is needed to confirm efficacy.

research Citrullination at the Inflammatory Skin Barrier

May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that baricitinib can counteract the cytokine-driven reduction of the enzyme PADI1 in human keratinocytes, which may help improve skin barrier function in atopic dermatitis by enabling epidermal differentiation.

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Community Join

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community What is this pigmentation around my follicles?

in Chat 29 upvotes 1 year ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 3 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

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Learn

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learn Fluocinolone

Is Fluocinolone a treatment for hair loss itself or just for calming scalp irritation? Fluocinolone acetonide is a prescription corticosteroid approved for inflammatory skin conditions, not for hair loss; no published human trial has measured hair regrowth with it, so at most it may help indirectly by calming an inflamed scalp.