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Glossary Hyperkeratosis

excessive thickening of skin's outer layer due to keratin

Hyperkeratosis is a condition where the outer layer of the skin, known as the stratum corneum, becomes excessively thick due to an overproduction of keratin. This can result in rough, scaly patches on the skin and is often seen in conditions like psoriasis or eczema. For professionals, it is important to note that hyperkeratosis can be a response to chronic irritation or inflammation and may require targeted treatments to manage the underlying cause.

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Research

5 / 1000+ results

research Intracorneal vacuoles in skin diseases with parakeratotic hyperkeratosis in the dog: a retrospective light‐microscopy study of 111 cases (1973–2000)

7 citations , February 2002 in “Veterinary Dermatology”

This study found that intracorneal vacuoles were common in various parakeratotic skin diseases in dogs, but large vacuoles were exclusively observed in congenital follicular parakeratosis.

research Skin Disorders in Overweight and Obese Patients and Their Relationship With Insulin

6 citations , February 2014 in “Actas Dermo-Sifiliográficas”

This study found that acanthosis nigricans and skin tags in nondiabetic, obese patients were significantly associated with higher insulin levels, suggesting they may serve as clinical markers of hyperinsulinemia.

research Obesity and the skin

128 citations , September 2011 in “British Journal of Dermatology”

Obesity is linked to various skin problems and may increase the risk of skin cancer.

research RASopathic Skin Eruptions during Vemurafenib Therapy

82 citations , March 2013 in “PLoS ONE”

In this study, vemurafenib was associated with a wide range of cutaneous side effects in patients with advanced melanoma, including photosensitivity and various skin and hair changes, necessitating regular dermatological management.

research Skin manifestations of obesity: a comparative study

45 citations , September 2011 in “Journal of the European Academy of Dermatology and Venereology”

This study found that obesity is associated with several skin conditions, such as striae and pseudoacanthosis nigricans, which may serve as markers of excessive weight.

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Community Join

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Skin Aging and Minox

5 upvotes 11 years ago

The conversation is about concerns over skin aging from using minoxidil for hair loss, with the user planning to use a minimal amount to avoid side effects. Other users suggest that overuse may cause temporary skin dryness but not actual aging, and emphasize proper application.

community Scalp Skin Barrier Health and Hair Follicle Cycling: A Potential Overlooked Connection

in Technology 4 months ago

The conversation discusses the importance of scalp skin barrier health in hair follicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.

community Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting

4 upvotes 1 year ago

Minoxidil can be effectively delivered through nanoemulsions containing eucalyptol or oleic acid, enhancing its diffusivity and targeting hair follicles. This contradicts the advice against mixing minoxidil with oils in topical formulations.

community Is there any good collagen to use for skin, nails, hair, and joints?

2 upvotes 1 month ago

Collagen supplements for improving skin, hair, nails, and joints. Recommendations include standard collagen peptide powder and Live Conscious collagen peptide, though some users doubt their effectiveness.

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Learn

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learn Keratin

learn Alpha Keratin

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

Clinics

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Experts

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35
SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin