Search
for

    Did you mean Hyperkeratosis?
    Glossary Hyperkeratosis

    excessive thickening of skin's outer layer due to keratin

    Hyperkeratosis is a condition where the outer layer of the skin, known as the stratum corneum, becomes excessively thick due to an overproduction of keratin. This can result in rough, scaly patches on the skin and is often seen in conditions like psoriasis or eczema. For professionals, it is important to note that hyperkeratosis can be a response to chronic irritation or inflammation and may require targeted treatments to manage the underlying cause.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Intracorneal vacuoles in skin diseases with parakeratotic hyperkeratosis in the dog: a retrospective light‐microscopy study of 111 cases (1973–2000) Veterinary Dermatology · 2002 · 7 citations
    2. Skin Disorders in Overweight and Obese Patients and Their Relationship With Insulin Actas Dermo-Sifiliográficas · 2014 · 6 citations
    3. Obesity and the skin British Journal of Dermatology · 2011 · 128 citations
    4. RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 82 citations
    5. Skin manifestations of obesity: a comparative study Journal of the European Academy of Dermatology and Venereology · 2011 · 45 citations
    6. Antigen presenting cells in the skin of a patient with hair loss and systemic lupus erythematosus. PubMed · 2009 · 9 citations
    7. Skin features in myotonic dystrophy type 1: An observational study Neuromuscular Disorders · 2015 · 8 citations
    8. Bacteria and fungi on the surface and within noninflamed hair follicles of skin biopsy specimens from horses with healthy skin or inflammatory dermatoses Veterinary Dermatology · 2005 · 7 citations
    9. Correction: RASopathic Skin Eruptions during Vemurafenib Therapy PLoS ONE · 2013 · 4 citations
    10. Unilateral nevoid hyperkeratosis of the nipple and areola in a Saudi female Our Dermatology Online · 2018 · 2 citations
    11. A Rare Case of Orthokeratotic Hyperkeratosis in a Kid Induced by Malassezial Dermatitis The Indian Veterinary Journal · 2024
    12. Skin manifestations and biophysical changes following weight reduction induced by bariatric surgery: A 2‐year prospective study The Journal of Dermatology · 2023
    13. 393 Skin manifestations and biophysical properties in patients with morbid obesity and changes after weight loss: A two-year prospective study Journal of Investigative Dermatology · 2023
    14. IL-17 axis is a significant driver of skin inflammation in Card14 mutant pityriasis rubra pilaris model mice Research Square (Research Square) · 2023
    15. Case Report: Bi-allelic missense variant in the desmocollin 3 gene causes hypotrichosis and recurrent skin vesicles Frontiers in genetics · 2022
    16. Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 -Deficient Mice Reveal the Importance of Palmitoylation in Hair and Skin Differentiation 2015 · 16 citations
    17. Murine Epidermal Ceramide Synthase 4 Is a Key Regulator of Skin Barrier Homeostasis Journal of Investigative Dermatology · 2020 · 15 citations
    18. Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice EMBO molecular medicine · 2014 · 81 citations
    19. Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function Cell death and disease · 2018 · 74 citations
    20. Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation American Journal Of Pathology · 2011 · 54 citations
    21. The Link Between Obesity and the Skin Frontiers in Nutrition · 2022 · 12 citations
    22. Lesions in the skin, intestine, and central nervous system induced by an antimetabolite of niacin. PubMed · 1986 · 12 citations
    23. Immunohistochemical Expression of Keratins in Normal Ovine Skin and in Chronic Dermatitis due to Sarcoptes scabiei Journal of comparative pathology · 2021 · 2 citations
    24. Skin Lesions in a Daclizumab-treated Patient with Multiple Sclerosis Journal of Interdisciplinary Medicine · 2019 · 1 citations
    25. Epidermis-specific ablation of claudin-1 in adult mice demonstrates the essential role of a tight junction barrier in skin homeostasis Journal of Dermatological Science · 2016 · 1 citations
    26. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin International Journal of Molecular Sciences · 2025
    27. Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin 2024
    28. Skin barrier, phenotypic and genotypic characterisation of autosomal recessive ichthyosis in TGM1‐deficient Jack Russell Terriers and response to topical ceramide Veterinary Dermatology · 2024
    29. 738 Cryo-EM and molecular dynamics of TRPV3 channel in activated state reveal structural features implicated in severe itch and hyperkeratosis 2023
    30. Respective Treatment Modalities with the Use of Combined Ingredients to Address Acne Prone Skin Journal of dermatology research and therapy · 2021