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      Stem Cells and the Niche: A Dynamic Duo

      research Stem Cells and the Niche: A Dynamic Duo

      333 citations, February 2010 in “Cell Stem Cell”
      Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
      Stem Cell Heterogeneity and Plasticity in Epithelia

      research Stem Cell Heterogeneity and Plasticity in Epithelia

      129 citations, May 2015 in “Cell Stem Cell”
      Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

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