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      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

      learn Saw Palmetto

      a natural and far less effective alternative to Finasteride

    Research

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      research Unique Amino Acid Signatures That Are Evolutionarily Conserved Distinguish Simple-Type, Epidermal, and Hair Keratins

      76 citations, December 2011 in “Journal of Cell Science”
      The study analyzed keratin sequences from various species, focusing on epidermal, simple-type epithelial, and hair keratins. It found that keratin domains have distinct amino acid compositions: hair keratins are rich in cysteines and prolines, epidermal keratins are abundant in glycine and phenylalanine but low in alanine, and simple-type epithelial keratins are enriched in acidic and basic residues. These differences are evolutionarily conserved and reflect the unique structural and functional roles of each keratin type. Additionally, cysteines and histidines, though rare, are frequently involved in de novo mutations in keratins, highlighting their significance in keratin function and mutation hotspots.
      Keratin Disorders: From Gene to Therapy

      research Keratin Disorders: From Gene to Therapy

      109 citations, September 2011 in “Human molecular genetics online/Human molecular genetics”
      New treatments targeting specific genes show promise for treating keratin disorders.
      Keratin and Skin Disorders

      research Keratin and Skin Disorders

      28 citations, April 1996 in “Cell biology international”
      Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

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