research Systematic Review: Interventions in Sickle Cell Disease-Related Priapism in Reducing Overall Morbidity, Recurrence, and Side Effects
More research is needed to find effective treatments for sickle cell disease-related priapism.
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5 / 221 results research Hair Cortisol Is a Potential Indicator of Adrenal Insufficiency in Individuals with Sickle Cell Disease
Hair cortisol may help identify adrenal insufficiency in sickle cell disease patients.
research Recurrent Priapism in a Sickle Cell Disease Patient Treated with Gonadotropin-Releasing Hormone Agonists: A Case Report
A 34-year-old male with sickle cell disease experienced recurrent ischemic priapism, unresponsive to standard treatments, including oral etilefrine and bicalutamide. As a last resort before considering penile prosthesis, he was treated with goserelin, a gonadotropin-releasing hormone (GnRH) agonist, which resulted in significant clinical improvement, cessation of stuttering priapism, and recovery of erectile function. The patient opted to continue hormonal therapy, avoiding surgery. This case highlights the potential of GnRH agonists in managing recurrent priapism in sickle cell patients, though long-term safety remains uncertain and warrants further study.
research Finasteride for Recurrent Priapism in Children and Adolescents with Sickle Cell Disease: Report of 5 Cases
Finasteride effectively reduced priapism episodes in children with sickle cell disease without side effects.
research Investigation of Parental Socioeconomic Status as a Determinant of Dietary Habits and Disease Severity of Sickle Cell Disease Children
Parental socioeconomic status doesn't improve dietary habits or reduce disease severity in children with sickle cell disease.
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5 / 25 resultscommunity CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?
CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.
community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits
Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.
community A year of fin+min(23yo), got my life back
A 23 year old user who has had success with finasteride and minoxidil, regaining their hair after losing it due to male pattern baldness. They also attribute part of the success to lifestyle changes such as eating better, exercising, sleeping well, and reducing smoking.
community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)
There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.
community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.
The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.