Sickle Cell Disease Complications and BMI Percentiles of Pediatric Patients

    Anuoluwapo Abisola Alaka, Ayobola Abolape Iyanda
    Studysummary This study explored the relationship between BMI percentiles and clinical severity in pediatric patients with different hemoglobin genotypes, finding significant BMI differences and associations with pain frequency, particularly noting that patients with HbSS experienced more pain than those with HbSC.
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    The study investigates the relationship between BMI percentiles and the severity of sickle cell disease (SCD) in pediatric patients. It found significant differences in body weight, height, and BMI among the genotypes HbAA, HbSC, and HbSS, with 5% of HbAA, 20% of HbSC, and 35.7% of HbSS in unhealthy BMI categories. The study also revealed a significant relationship between BMI percentiles and pain frequency in SCD patients, with HbSS patients experiencing more frequent pain than HbSC patients. Additionally, priapism was more common than leg ulcers among SCD complications in the region. The findings suggest that SCD affects BMI percentiles and that there is a bias in pain frequency distribution between the two hemoglobinopathies.
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