21 citations
,
October 2017 in “Cell death and disease”
This study found that the absence of the stress-responsive protein Sesn2 increased haircell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.
3 citations
,
July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study used scRNA-Seq to map the transcriptional changes during zebrafish haircell regeneration, revealing distinct phases including injury response, transient regeneration gene activation, and reactivation of developmental programs.
44 citations
,
March 2016 in “Frontiers in cellular neuroscience”
In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect haircells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.
Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.
A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.
User spent 23 years on Finasteride with side effects like weight gain and reduced libido. Switched to topical Finasteride, side effects reduced and waiting for results.
New hair loss treatments like Breezula and a version of Minoxidil for hair regrowth are in advanced trials and may be available in a few years. Clascoterone and other treatments like oral and topical Minoxidil, Finasteride, and Dutasteride are also discussed, with some users experiencing side effects from Finasteride.
Hair loss can persist despite using treatments like finasteride, dutasteride, and minoxidil due to factors like genetic sensitivity, incomplete DHT blockage, and other hormonal influences. Individual responses vary, and some may require a combination of treatments to stabilize hair loss.