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research LncRNA MSTRG.14227.1 regulates the morphogenesis of secondary hair follicles in Inner Mongolia cashmere goats via targeting ADAMTS3 by sponging chi-miR-433

3 citations , December 2024 in “Journal of Animal Science”

In this study, researchers identified the lncRNA MSTRG.14227.1 in cashmere goats and found it inhibits the morphogenesis of secondary hair follicles by interacting with the chi-miR-433/ADAMTS3 signaling axis, affecting cashmere yield and quality.

research Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep

1 citations , January 2024 in “International journal of molecular sciences”

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

research Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats

14 citations , April 2022 in “Functional & Integrative Genomics”

This study identified specific miRNAs and mRNAs involved in the development of secondary hair follicles in cashmere goats, particularly noting a targeted relationship between chi-miR-30e-5p and DLL4.

research Spatiotemporal secondary hair follicle development in the Lanyu pig (Sus scrofa taivanus): a novel pelage hair follicle model

August 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study characterizes the secondary hair follicles in the Lanyu pig, an indigenous breed sharing similarities with human vellus hair follicles, suggesting its relevance as a model for researching hair follicle-mediated skin regeneration and enhancing translation to human wound healing.

research Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats

127 citations , March 2016 in “PLoS ONE”

This study found that transcriptome profiling of cashmere goat skin revealed key genes and pathways involved in hair follicle initiation, differentiation, and maturation, which are critical for improving fleece production.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Secondary shedding, 6 months into oral minoxidil/finasteride 3mg chewables

55 upvotes 4 months ago

The user experienced significant hair regrowth and increased density after six months of using oral minoxidil and finasteride chewables, despite going through a secondary shedding phase. The only side effect mentioned was restlessness, and the user feels healthier overall.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community It’s all about the stem cells…

53 upvotes 4 years ago

Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

community Haircafe slams pp405 presentation. Are results really that bad?

64 upvotes 5 months ago

PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

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Learn

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learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Follicusan

learn Hair Transplant

Can hair be taken from other parts of the body for hair transplantation? Body hair can be used for transplantation but is generally a secondary option.
What is a hair transplant? A hair transplant is a surgical procedure that relocates hair follicles to areas of thinning.

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