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    GlossaryAtypical Antipsychotics (Second-Generation Antipsychotics)

    medications treating psychiatric conditions with fewer movement disorder side effects

    Atypical Antipsychotics, also known as Second-Generation Antipsychotics (SGAs), are a class of medications used to treat psychiatric conditions such as schizophrenia and bipolar disorder. Unlike first-generation antipsychotics, they are less likely to cause movement disorders like tardive dyskinesia and often have a broader range of action, affecting both dopamine and serotonin receptors in the brain.

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      Summary of Findings on Psychotropic Medications

      research Summary of Findings on Psychotropic Medications

      December 2006 in “The Brown University Psychopharmacology Update”
      Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.
      Reporting on Adverse Clinical Events

      research Reporting on Adverse Clinical Events

      March 2021 in “Clin-Alert”
      The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
      Forum

      research Forum

      August 2012 in “Pharmaceutical Medicine”
      The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

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