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Steroid 5 Alpha-Reductase 1

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The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

17 citations, October 2003 in “Brazilian Journal of Medical and Biological Research”

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

research Update on Idiopathic Hirsutism: Diagnosis and Treatment

6 citations, July 2013 in “Acta Clinica Belgica”

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase

29 citations, July 2009 in “BJU international”

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

research Intracrine Androgen Biosynthesis, Metabolism, and Action Revisited

131 citations, September 2017 in “Molecular and Cellular Endocrinology”

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

research Ovine Placental Steroid Synthesis and Metabolism in Late Gestation

9 citations, April 2018 in “Biology of reproduction”

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

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community Anyone experienced weight gain on dutasteride?

in Finasteride/Dutasteride 6 upvotes 2 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community What should I expect from dutasteride?

in Finasteride/Dutasteride 2 upvotes 3 years ago

The user tried Minoxidil, PRP, Hair Carboxytherapy, and topical Dutasteride with limited success and is now on oral Dutasteride. They are experiencing some hair loss reduction but no significant density improvement, leading to feelings of depression.

community Dutasteride Literally Saves Your Hair

in Finasteride/Dutasteride 98 upvotes 6 months ago

Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

community Why does it seem everyone favors finasteride over dutasteride?

in Female 62 upvotes 7 months ago

The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 8 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

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