73 citations
,
April 2019 in “Experimental Dermatology”
This review explores the hair follicle microbiome's interaction with the immune system, discussing its potential clinical implications for scalp health and disease but reports no new clinical results.
28 citations
,
March 1973 in “The Journal of Clinical Endocrinology & Metabolism”
This study found that hair follicles from balding men show significant metabolic differences compared to those from non-balding individuals, particularly in their ability to process dehydroepiandrosterone.
24 citations
,
April 2006 in “Journal of the American Academy of Dermatology”
This study reported that HSP27 protein shows varied expression in human scalp hair follicles across anagen, catagen, and telogen stages, suggesting a role in hair follicle biology.
How does sh-Polypeptide-7 help stimulate hair follicle activity or reduce scalp inflammation?sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.
The conversation discusses the importance of scalp skin barrier health in hair follicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.
Switching milk brands cleared scalp inflammation and other symptoms, but hair shedding continues. The user hopes shedding will stop as hair cycles progress.
Hair/scalp cloning for unlimited transplants is likely a decade away, with prior transplants not significantly affecting future options. Advances in AI and research in wound-induced hair neogenesis are promising, but infrastructure and technology constraints remain challenges.
A healthy scalp barrier is crucial for hair growth, and ceramides may play a key role in maintaining it. The conversation suggests that focusing on scalp health, alongside treatments like Minoxidil, Finasteride, and RU58841, could improve hair follicle health.
Dutasteride significantly reduces DHT levels in hair follicles, potentially more effectively than previously thought. The discussion highlights differences in DHT measurements and the impact on hair loss treatment.