Search
for

    Glossary ROCK inhibitor

    blocks enzymes involved in cell contraction and motility

    A ROCK inhibitor, also known as a Rho-associated kinase inhibitor, is a type of drug that blocks the activity of Rho-associated kinases (ROCKs). These enzymes play a crucial role in various cellular functions, including contraction, motility, proliferation, and apoptosis. By inhibiting ROCKs, these drugs can help treat conditions like hypertension, glaucoma, and even promote hair growth in cases of alopecia by improving blood flow and reducing inflammation.

    Related Terms

    Research 10 of 443

    1. ROCK inhibitor Y-27632 maintains the propagation and characteristics of hair follicle stem cells. PubMed · 2018 · 12 citations
    2. Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632 Frontiers in cell and developmental biology · 2021 · 16 citations
    3. 557 Short-term Rho-associated kinase inhibitor treatment accelerates primary keratinocyte growth without affecting the characteristics of the stem cell population Journal of Investigative Dermatology · 2022
    4. Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector Stem Cell Research & Therapy · 2013 · 18 citations
    5. Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures Stem Cells and Development · 2013 · 15 citations
    6. Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets Experimental Dermatology · 2022 · 3 citations
    7. Efficient establishment of an optimized culture condition for cashmere goat primary hair follicle stem cells 2023
    8. Regulatory T cells modulate bone marrow stromal cell osteogenesis by activating ROCK-myosin axis and cell contractility 2026
    9. Differentiation of Human Pluripotent Stem Cells Into Definitive Endoderm Cells in Various Flexible Three-Dimensional Cell Culture Systems: Possibilities and Limitations Frontiers in Cell and Developmental Biology · 2021 · 13 citations
    10. Curcumin derivatives inhibit testicular 17β-hydroxysteroid dehydrogenase 3 Bioorganic & Medicinal Chemistry Letters · 2010 · 19 citations
    All research results →

    Community 1 of 2

    1. Totally anecdotal but I hit rock bottom and totally abandoned my hair regiment for 3 months (vitamins, minoxidil) and noticed no difference. Reddit · 15 Sept 2025
    All community results →

    Learn

    — no results

    Try a deeper search in learn →