November 2023 in “Bioengineering” This study found that autologous micrografts using AMT® technology effectively improved symptoms and mobility in patients with early-stage knee osteoarthritis, demonstrating safety and potential benefits at 1- and 6-months post-procedure.
This review discusses the use of umbilical cord blood in regenerative medicine, focusing on collection, banking processes, and ethical considerations, without presenting new clinical results.
January 2022 in “Sustainable development goals series” The document concludes that significant investment in agricultural innovation is necessary to achieve global food security and nutrition.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This promotional text for Kudo Zero Sugar Collagen Support Gummies highlights their potential benefits for skin appearance but reports no new clinical research findings.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes Kudo Anti-Aging Gummies, which are promoted as a natural supplement designed to reduce wrinkles, enhance hair and nail health, and improve skin appearance by restoring collagen, with results purportedly visible within 1-2 months.
14 citations
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May 2013 in “American Journal of Physiology-endocrinology and Metabolism” This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.
1 citations
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November 2024 in “Journal of Dermatological Treatment” Significant hair regrowth doesn't always mean complete hair recovery in alopecia areata.
This study introduced a novel framework called SL-HyDE that significantly improved zero-shot dense retrieval accuracy in medical information retrieval without relying on labeled data.
November 2022 in “Journal of Investigative Dermatology” This study found that MPZL3 knockout mice showed reduced dermal white adipose tissue and increased sebocyte proliferation, suggesting a regulatory role for MPZL3 in lipid metabolism balance between adipocytes and sebocytes.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this N=1 case study, a long-term zero-carbohydrate diet adult male experienced an increase in fasting plasma ascorbic acid from 0.1 mg/dL to 2.0 mg/dL within two months of daily 1 g vitamin C supplementation, along with subjective health improvements.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this N=1 case study, researchers observed that a 1 g daily dose of vitamin C successfully elevated plasma vitamin C levels in an adult male following a zero-carbohydrate diet, with reported improvements in some health parameters but no gastrointestinal side effects.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This publication presents a library of geometric medicines designed to selectively target pathogenic bacteria and fungi with high precision while minimizing ecological harm, available for free on a non-commercial basis.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This publication presents a library of precision geometric medicines that reportedly kill harmful bacteria and fungi while sparing beneficial organisms, using a delivery system that targets pathogens specifically and avoids ecological harm.
January 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that coated microneedles promoted drug release effectively, comparable to marketed minoxidil solutions, with stable performance over 30 days at high temperatures.
1 citations
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July 2024 in “Journal of Investigative Dermatology” MPZL3 protein affects hair growth cycles and could help manage hair loss.
April 2023 in “Journal of Investigative Dermatology” This study suggests that MPZL3, a mitochondrially localized protein, may play an integral role in regulating hair follicle cycles, with potential therapeutic implications for hair growth disorders if findings translate to humans.
April 2023 in “Journal of Investigative Dermatology” This study found that MPZL3 plays a crucial role in controlling sebaceous gland size and sebocyte proliferation in mice and humans, implicating its potential involvement in skin disorders like acne and psoriasis.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that Myelin Protein Zero-like 3 plays a crucial role in hair follicle cycling by regulating anagen and catagen phases, mediated through mitochondrial signaling mechanisms in both human and murine hair follicles.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that MPZL3 plays a crucial role in regulating the hair cycle clock in mice, with its absence leading to accelerated hair follicle cycling and suggesting potential therapeutic pathways for alopecia treatment.
March 2024 in “Chinese Chemical Letters” In this study, researchers demonstrated that zero valence fluorescent gold nanoclusters can be biosynthesized in damaged skin and inhibit hair follicle regeneration by affecting the NFκB inflammatory response pathway, suggesting potential as a treatment for hypertrichosis related to skin injury.
10 citations
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August 2022 in “Bulletin of Mathematical Biology” This study demonstrated that the Turing bifurcation, typically a pitchfork bifurcation under zero-flux conditions, becomes transcritical under fixed boundary conditions, highlighting the importance of considering boundary condition variations in morphogenetic analyses.
1 citations
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October 2018 in “Infectious diseases in clinical practice” This case report documents what may be the second reported instance of azithromycin-induced agranulocytosis, highlighted by a sudden drop to zero in absolute neutrophil count in a 67-year-old man.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study indicates that MPZL3 negatively regulates sebaceous gland size in mice by controlling sebocyte proliferation, with implications for disorders like acne and psoriasis.
17 citations
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April 2017 in “PLoS ONE” This study found that neural crest-derived hair follicle cells in mice can differentiate into osteoblast-like cells, suggesting a potential application for bone regenerative therapies.
June 2026 in “HAL (Le Centre pour la Communication Scientifique Directe)” This infographic compares the safety profiles of SH‑1, a cosmetic ingredient, which showed no systemic absorption, and PP405, an investigational drug with dose-dependent systemic uptake and potential threshold breaches, highlighting differences in safety between cosmetic and investigational substances according to this report.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
73 citations
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January 2021 in “Engineered Regeneration” This review discusses the use of metal-based biomaterials in wound repair, highlighting their potential to accelerate skin regeneration, but reports no new clinical results.
18 citations
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February 2025 in “Drug Delivery and Translational Research” This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.
13 citations
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July 2017 in “Biopolymers” This study presents recombinant human hair keratins K31 and K81, observing novel nanostructures from their self-assembly and emphasizing disulfide crosslinking's role in this process.
11 citations
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December 2011 in “International journal of pharmaceutics” In this study, brief ultrasound exposure reduced the follicular contribution to hydrocortisone absorption while significantly increasing total skin permeability, likely due to removal of the upper stratum corneum.