Finding functions for unknown GPCRs is hard but key for making new drugs.
Monocyclic aromatic compounds are important for developing various drugs and treatments.
1 citations,
September 2003 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” Transdermal fluoxetine is less effective in cats, clomipramine may help with feline alopecia, younger dogs often start fights, dietary changes can reduce cribbing in horses, negative aggression tests in shelter dogs predict good behavior, many older cats show cognitive issues, and fluoxetine or paroxetine can improve canine anxiety.
1 citations,
April 1987 in “American Journal of Nursing” Some drugs can cause serious side effects, like hypoglycemia from mix-ups, skin reactions, or depression, and while penicillamine may help rheumatoid arthritis more than auranofin, it has more severe side effects.
October 2024 in “Current Trends in Biotechnology and Pharmacy” The shampoo effectively promotes hair growth and is halal-compliant.
July 2024 in “Science and Culture” Thuja orientalis L. has many health benefits and could be used in new medicines.
April 2024 in “Proceedings” People with alopecia areata often have lower iron levels than healthy people.
Doctors should consider Netherton syndrome in patients with chronic skin and hair issues to avoid misdiagnosis.
October 2023 in “Plant Archives/Plant archives” Hibiscus rosa-sinensis is effective and safe for use in herbal soaps and hair oils, promoting skin and hair health.
September 2023 in “Cureus” Nails can reveal important health information about skin and body conditions.
Higher EULAR/ACR scores in SLE patients predict more organ damage.
Excluding alopecia and mucous membrane components from the CLASI-A score reduces its effectiveness in capturing important disease activity.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” Patients with alopecia areata face challenges accessing Janus kinase inhibitors, but some see positive results.
January 2023 in “Acta historiae medicinae, stomatologiae, pharmaciae, medicinae veterinariae” Historical baldness remedies were varied and often based on superstition.
December 2022 in “Journal of medical sciences and health” Examining nail biopsies is useful for diagnosing nail diseases.
September 2022 in “IP Indian journal of clinical and experimental dermatology” An 8-year-old girl has a rare genetic disorder causing complete, irreversible hair loss and skin bumps.
June 2022 in “Rheumatology research” Lupus can be a rare cause of high calcium levels in the blood.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical treatments led to hair regrowth in a man with linear morphea.
September 2019 in “Asian Journal of Pharmaceutical and Clinical Research” Teak seed extract is safe and reduces pain in mice.
The document concludes that diagnosing female hair loss requires careful examination, with treatments varying by condition and psychological support often necessary.
June 2019 in “Journal of evolution of medical and dental sciences” Dermoscopy is useful for tracking alopecia areata treatment, with yellow dots and new vellus hairs being good indicators of hair regrowth.
May 2019 in “Australasian Journal of Dermatology” New insights in skin conditions show a complex link between certain moles and melanoma, improved hair loss treatments, and the need to identify different types of lupus.
April 2019 in “Endocrinology and Metabolism Clinics of North America” Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.
August 2018 in “Online journal of neurology and brain disorders” Sodium valproate is effective in treating epilepsy, especially in patients who don't respond to other medications.
July 2018 in “Nasza Dermatologia Online” Frontal fibrosing alopecia and ulerythema ophryogenes may be related and can evolve from one to the other.
March 2018 in “Suez Canal University Medical Journal” New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
September 2017 in “Journal of Investigative Dermatology” The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.
September 2017 in “Journal of Investigative Dermatology” Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.
September 2017 in “Journal of Investigative Dermatology” The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
September 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.