research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration
Pro-IGF-II improves muscle repair in old mice.
Search
for
Sort by
Research
300-330 / 367 results 
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research The Optimal Indication for Testosterone Replacement Therapy in Late-Onset Hypogonadism
Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.
research Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling
Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.
research The Endoscopic Brow Lift
The document concludes that the endoscopic brow lift is a less invasive cosmetic surgery that requires careful technique and patient selection to achieve lasting, aesthetically pleasing results.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Analogs of Human Genetic Skin Disease in Domesticated Animals
Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.
research Facial Feminization Surgery and Facial Gender Confirmation Surgery
The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.
research Role of Metformin in Polycystic Ovary Syndrome (PCOS): Related Infertility
Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
research Deep Learning-Based Dermatological Condition Detection: A Systematic Review With Recent Methods, Datasets, Challenges, and Future Directions
Deep learning helps detect skin conditions and is advancing dermatology diagnosis and treatment.
research Industry Update: The Latest Developments in the Field of Therapeutic Delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research Multiple Endocrine Defects in Adult-Onset Sprouty1/2/4 Triple Knockout Mice
Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.
research Changes In Eyebrow Position Following Blepharoptosis Surgery
Blepharoptosis surgery usually lowers the eyebrows, especially near the nose.
research Myotonic Dystrophy Type 1: Enhancing Patient Management Through Genetic and Multisystem Studies
There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Effect of Decellularisation Methods on Methacryloyl-Substituted Placental ECM Hydrogels
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
research Cosmetic Plastic Surgery Trends and Procedures for Male Patients
More men are getting cosmetic surgery, with nose jobs and hair transplants being popular, and choosing a qualified surgeon is important.
research Endoscopic Forehead and Brow Lift
EFBL offers hidden incisions, faster recovery, and fewer risks, but may raise hairline and cost more.
research Repigmentation by Combined Narrow-Band Ultraviolet B/Adipose-Derived Stem Cell Transplantation in the Mouse Model: Role of Nrf2/HO-1-Mediated Ca2+ Homeostasis
Combining narrow-band ultraviolet B light and stem cell transplantation helps repigmentation in vitiligo by maintaining calcium balance in mice.
research Pathology of Mouse Models of Accelerated Aging
Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
research Intermittent Treatment with Farnesyltransferase Inhibitor and Sulforaphane Improves Cellular Homeostasis in Hutchinson-Gilford Progeria Fibroblasts
Alternating treatment with two drugs could help cells in a rapid aging disease.
research Opposing Impacts on Healthspan and Longevity by Limiting Dietary Selenium in Telomere Dysfunctional Mice
Low selenium levels can extend lifespan but worsen health issues.
research A Comprehensive Review of Acne Vulgaris
Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
research PCSK9: From Nature's Loss to Patient's Gain
Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.
research Case Report: Heterozygous Mutation in HTRA1 Causing Typical Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.
research Epidermolysis Bullosa Simplex in Children with De Novo Pathogenic Variants Disturbing KRT14
Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Smart Microneedles for Therapy and Diagnosis
Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
research Autotaxin–Lysophosphatidic Acid–LPA3 Signaling at the Embryo-Epithelial Boundary Controls Decidualization Pathways
LPA3 signaling in the uterus is crucial for placental formation and fetal development.