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Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

2021 saw a slow return to normalcy and increased scientific engagement despite COVID-19 challenges.

Cialis and Finasteride could be repurposed to treat aggressive melanoma.

Androgens play a key role in causing alopecia by changing the hair growth cycle.

Researchers developed a new skin patch that delivers more finasteride into the skin, potentially improving treatment for hair loss and prostate issues.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.

Using tissue adhesive in hair transplants improves results and patient satisfaction, with fewer complications.

Minoxidil decreases LH expression, while hydralazine has mixed effects on prolyl and lysyl hydroxylase activities.

Finasteride potentially treats hair loss by reducing DHT production.

The study suggests computer-assisted analysis of scalp biopsies could improve hair loss diagnosis but needs more validation.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.

A defective gene causes hair loss and taste insensitivity in BTBR mice.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.

Combining microsurgery with craniofacial reconstruction improves aesthetic results and reduces harm to the area where tissue is taken from.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Exposure to Corexit dispersants during the oil spill cleanup was linked to increased respiratory and eye irritation symptoms in workers.