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The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

No cure for female pattern hair loss, but various effective treatments exist.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Melatonin solution helps treat hair loss in men and women.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.

Nanoemulsions improve stability and delivery of active ingredients in cosmetics for skin and hair care.

Obesity increases the risk of skin infections, inflammatory conditions, and melanoma, but not basal cell carcinoma.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.

Hair color is determined by different melanins and changes with age.

Alternative treatments show promise for hair growth beyond traditional methods.