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Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Vitamin D receptor is crucial for starting hair growth after birth.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Avoiding certain nutrients and drugs may help manage pemphigus.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.

Parathyroid hormone-related protein helps control hair growth phases in mice.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.